16939-11-0Relevant academic research and scientific papers
Room-temperature photoinduced direct C-H-arylation via base-promoted homolytic aromatic substitution
Budén, María E.,Guastavino, Javier F.,Rossi, Roberto A.
, p. 1174 - 1177 (2013)
Conceptually different approach toward biaryl syntheses by photoinduced direct C-H arylation of benzene and thiophene in the presence of t-BuOK is reported. The reaction proceeds through photo- and base-promoted homolytic aromatic substitution. The o-, m- and p- substituted ArI, as well as the electron-donating and electron-withdrawing nature of the substituents were found be good to excellent substrates. Heteroaryl, ArBr, ArCl and double C-H arylation were successfully achieved.
