1694-47-9

Usage

Type of compound

Fluorescent dye

Usage

Staining biological tissues and cells

Derivative of

Pyridinium iodide

Contains

Diethylamino group and styryl group

Responsible for

Fluorescent properties

Usage in research

Molecular biology and biochemistry as a fluorescent probe for visualizing cellular structures and processes

Medical applications

Diagnostics and imaging

Upstream product

• 872-73-1 N-methyl-2-methylpyridinium iodide 
• 120-21-8 4-Diethylaminobenzaldehyde 
• 109-06-8 α-picoline 

Downstream Products

• 1581708-29-3 2-[2-(4-diethylaminophenyl)vinyl]-1-methyl-pyridiniumnaphthalene-2-sulfonate 

Relevant academic research and scientific papers

Growth and characterization of an organic single crystal: 2-[2-(4-Diethylamino-phenyl)-vinyl]-1-methyl-pyridinium iodide

Optically transparent crystal of the organic salt DEASI (2-[2-(4-Diethylamino-phenyl)-vinyl]-1-methyl-pyridinium iodide) has been synthesized by using knoevenagel condensation reaction method. The synthesized material has been purified by successfully recrystallization process. Single crystals of DEASI have been grown by slow evaporation technique at room temperature. The solubility of the title material has been determined at different temperature in acetonitrile/methanol mixture. The cell parameters and crystallinity of the title crystal were determined by single crystal XRD. The powder diffraction was carried out to study the reflection plane of the grown crystal and diffraction peaks were indexed. The presence of different functional groups in the crystal was confirmed by Fourier transform infrared (FTIR) analysis. 1H NMR spectrum was recorded to confirm the presence of hydrogen nuclei in the synthesized material. The optical property of the title crystal was studied by UV-Vis-NIR spectroscopic analysis. The melting point and thermal property of DEASI were studied using TGA/DSC technique. The Vicker's hardness (Hv) was carried out to know the category. The dielectric constant and dielectric loss of the compound decreases with an increase in frequencies. Chemical etching studies showed that the DEASI grows in the two dimensional growth mechanisms. The Kurtz-Perry powder second harmonic generation (SHG) test has done for title crystal.

Synthesis, growth, crystal structure, spectral, thermal, mechanical and optical studies of stilbazolium derivative single crystal: 2-[2-(4-Diethylamino- phenyl)-vinyl]-1-methyl-pyridinium naphthalene-2-sulfonate (DESNS)

Single crystals of organic optical material, 2-[2-(4-Diethylamino-phenyl)- vinyl]-1-methyl-pyridinium naphthalene-2-sulfonate (DESNS) (15 × 10 × 9 mm3) were grown by a slow evaporation technique at room temperature using methanol-acetonitrile (1:1) mixed solvent. The molecular structure of the grown crystal was confirmed by single crystal X-ray diffraction studies, and it belongs to orthorhombic system with space group Pbca and the unit cell dimentions are a = 11.5148(3) A?, b = 15.4352(4) A?, c = 27.2187(7) A?, Z = 8. The crystallinity of the title crystals was confirmed from the powder XRD pattern. The presence of functional groups of the title crystal was confirmed from the FTIR spectral studies. The transparent range and cut off wavelength of the grown crystal was studied by the UV-Vis-NIR spectroscopic analysis. The mechanical properties and thermal behavior of the grown crystals were studied from Vickers microhardness test and TG/DTA.

Solid-state fluorescence of pyridinium styryl dyes

1-Alkyl-2-[4-(diethylamino)styryl]pyridinium salts showed fluorescence maxima at around 650 nm in the solid state depending on the alkyl group and counter anion. 1-Butyl-2-[4-(diethylamino)styryl]pyridinium bis(perfluorobutylsulfonyl)imide exhibited the fluorescence maximum at 652 nm with the highest quantum yield 0.16 in the crystalline form. The single X-ray crystallography suggests that this compound exhibits isolated dimer-type packing leading to fluorescence in the solid state.

RNA-selective probes for live cell imaging of nuclear structure and function

The present invention is directed to fluorescent compounds and methods of making said compounds that selectively bind to cellular RNA. The fluorescent compounds of the present invention are useful for live cell imaging applications.

Development of fluorescence probes based on stilbazolium salts for monitoring free radical polymerization processes

A series of 1-methyl-2-(4-aminostyryl)pyridinium perchlorates and iodides were investigated as fluorescent probes for the monitoring of the progress of free radical polymerization. The study on the changes in the fluorescence intensity and spectroscopic shifts of studied compounds were carried out during thermally initiated polymerization of methyl methacrylate and during photoinitiated polymerization of a 2-ethyl-2-(hydroxymethyl)propane-1,3-diol triacrylate (TMPTA)-1-methylpyrrolidin-2-one (MP) mixture. The purpose of these studies was to find a relationship between the changes in the shape and intensity of probe fluorescence and degree of monomer conversion into polymer. The polymer formation was estimated gravimetrically or by the measurement of the degree of monomer double bond disappearance using FTIR spectroscopy.