1694-97-9

Usage

Uses

Used in Biochemical Research:
N-(2,4-DINITROPHENYL)-L-VALINE is used as a labeling agent for proteins and peptides to facilitate their detection and analysis in biochemical studies. The presence of the 2,4-dinitrophenyl group enhances the compound's visibility and allows for the tracking of biomolecules within complex biological systems.
Used in Enzymatic Assays:
DNVA serves as a substrate in enzymatic assays, enabling the evaluation of enzyme activity and specificity. Its unique structure allows researchers to monitor enzymatic reactions and gain insights into the mechanisms of action of various enzymes.
Used in Drug and Pharmaceutical Development:
N-(2,4-DINITROPHENYL)-L-VALINE is employed in the development of drugs and pharmaceuticals, particularly in the design of novel therapeutic agents. Its interaction with biological systems aids in the identification of potential drug targets and the optimization of drug candidates for improved efficacy and safety.
Used in the Study of Biological Processes and Pathways:
DNVA is used as a research tool to investigate various biological processes and pathways. Its ability to interact with biological systems allows researchers to explore the roles of specific proteins and peptides in cellular functions and disease mechanisms, contributing to a deeper understanding of biological systems and the development of targeted therapies.

InChI:InChI=1/C11H13N3O6/c1-6(2)10(11(15)16)12-8-4-3-7(13(17)18)5-9(8)14(19)20/h3-6,10,12H,1-2H3,(H,15,16)

Upstream product

• 72-18-4 L-valine 
• 70-34-8 2,4-Dinitrofluorobenzene 
• 10547-33-8 N-(2,4-dinitrophenyl)-D,L-valine 
• 584-48-5 2,4-dinitrobromobenzene 
• 97-00-7 1-chloro-2,4-dinitro-benzene 

Relevant academic research and scientific papers

Efficient nucleophilic substitution reaction of aryl halides with amino acids under focused microwave irradiation

The nucleophilic substitution reaction of 2,4-dinitrofluorobenzene with amino acids was complete, under microwave iradiation, within 40 s with yields up to 93%, which are far superior to those obtained under conventional heating. (C) 2000 Elsevier Science Ltd.

Direct resolution of optically active isomers on chiral packings containing ergoline skeletons. 5. Enantioseparation of amino acid derivatives

A new procedure for ergot alkaloid-based chiral stationary phase preparation is described. Synthesis is based on bonding the allyl derivative of terguride to mercaptopropylsilanized silica gel. The packing exhibits higher content of chiral selector, stability, reproducibility, and enantioselectivity toward amino acids compared to that previously studied. The chromatographic behavior of amino acids with different side chains and substituent groups is investigated in order to obtain a deeper insight into the enantiodiscriminative mechanism as well as to determine the limitations and strengths of terguride as a chiral selector for this class of compounds. A variety of factors, including mobile phase parameters such as pH, ionic strength, content and nature of organic modifier, and temperature, are examined. A new procedure for ergot alkaloid-based chiral stationary phase preparation is described. Synthesis is based on bonding the allyl derivative of terguride to mercaptopropylsilanized silica gel. The packing exhibits higher content of chiral selector, stability, reproducibility, and enantioselectivity toward amino acids compared to that previously studied. The chromatographic behavior of amino acids with different side chains and substituent groups is investigated in order to obtain a deeper insight into the enantiodiscriminative mechanism as well as to determine the limitations and strengths of terguride as a chiral selector for this class of compounds. A variety of factors, including mobile phase parameters such as pH, ionic strength, content and nature of organic modifier, and temperature, are examined.