16944-14-2

Basic information

• Product Name: BOC-TYR-OH DCHA
• Synonyms: N-TERT-BUTOXYCARBONYL-L-(-)-TYROSINE DICYCLOHEXYLAMINE SALT;BOC-L-TYROSINE DCHA;BOC-TYR-OH DCHA;N-[(tert-butoxy)carbonyl]-L-tyrosine, compound with dicyclohexylamine (1:1)
• CAS NO: 16944-14-2
• Molecular Formula: C₁₂H₂₃N*C₁₄H₁₉NO₅
• Molecular Weight: 462.62
• EINECS: 241-013-3
• Mol File: 16944-14-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 484.9°Cat760mmHg
• Flash Point: 247.1°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 3.23E-10mmHg at 25°C
• CAS DataBase Reference: BOC-TYR-OH DCHA(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-TYR-OH DCHA(16944-14-2)
• EPA Substance Registry System: BOC-TYR-OH DCHA(16944-14-2)

Safety Data

• Hazardous Substances Data: 16944-14-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H19NO5.C12H23N/c1-14(2,3)20-13(19)15-11(12(17)18)8-9-4-6-10(16)7-5-9;1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h4-7,11,16H,8H2,1-3H3,(H,15,19)(H,17,18);11-13H,1-10H2/t11-;/m0./s1

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 60-18-4 L-tyrosine 
• 101-83-7 N-cyclohexyl-cyclohexanamine 

Downstream Products

• 100350-69-4 Boc-Tyr-Val-Arg(NO₂)-Lys(Z)-OMe 
• 100103-12-6 Boc-Tyr-Arg(NO₂)-D-Lys(Z)-OMe 
• 96356-48-8 Boc-Tyr-Arg(NO₂)-Lys(Z)-OMe 
• 120219-33-2 Boc-Tyr-OPac 
• 14623-69-9 H-Tyr-Gly-OMe*HCl 
• 80727-49-7 cyclo-Met⁵-Enkephalin 
• 77591-04-9 Boc-Gly-Phe-Leu-Tyr-Gly-OMe 
• 80727-52-2 Boc-Gly-Phe-Met-Tyr-Gly-OMe 
• 80727-53-3 Boc-Gly-Phe-Leu-Tyr-Gly-N₂H₃ 
• 80727-54-4 Boc-Gly-Phe-Met-Tyr-Gly-N₂H₃ 
• 75975-40-5 cyclo-Leu⁵-Enkephalin 
• 100103-13-7 Boc-Tyr-Arg(NO₂)-D-Lys(Z)-OH 
• 100017-97-8 cyclo<-Tyr-Arg(NO2)-D-Lys(Z)-Glu(OBzl)-D-Val-> 
• 100017-96-7 cyclo<-Tyr-Arg(NO2)-D-Lys(Z)-Asp(OBzl)-D-Val-> 

Relevant articles and documents

Peptide synthesis in aqueous solution. IV. Preparation and properties of [p-(benzyloxycarbonyloxy)phenyl]dimethylsulfonium methyl sulfate, [p-(t-butoxycarbonyloxy)phenyl]dimethylsulfonium methyl sulfate and [p-(9-fluorenylmethyl-oxycarbonyloxy)phenyl]dimethylsulfonium methyl sulfate as water-soluble N-acylating reagents

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Use of 2-pyrimidine thiol carbonates as acylating agents for amino or imino containing compounds

Thiolcarbonates represented by the formula, SPC1 Wherein R1 and R2 are individually a hydrogen atom or a methyl group, and R3 is a straight chain or branched chain saturated or unsaturated alkyl group having 1 to 5 carbon atoms or is a benzyl or benzhydryl group which may be nuclear substituted, are quite useful for protecting the amino or imino groups of amines, hydrazines, amino acids and peptides with groups of the formula EQU1 The thiolcarbonates can be easily produced by reacting an alkali metal salt of 2-mercaptopyrimidine with phosgene, and reacting the resulting thiolchloroformate with an alcohol (R3 OH), or by reacting a 2-mercaptopyrimidine with a halocarbonic acid ester.