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169448-17-3

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  • 1-Piperazinecarboxylicacid, 2-(2-hydroxyethyl)-, 1,1-dimethylethyl ester, (2S)- Manufacturer/High quality/Best price/In stock

    Cas No: 169448-17-3

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169448-17-3 Usage

Description

(S)-tert-butyl 2-(2-hydroxyethyl)piperazine-1-carboxylate, also known as tert-butyl glycine tert-butyl ester, is a piperazine derivative that is a derivative of glycine. This chemical compound features a tert-butyl group attached to the alpha carbon of the glycine moiety, which imparts steric hindrance and affects the molecule's reactivity. It is recognized for its utility as a chiral auxiliary in organic synthesis, facilitating asymmetric induction and impacting the stereochemistry of reaction products. Moreover, it holds promise in medicinal chemistry, particularly for the development of innovative drugs and therapeutic agents.

Uses

Used in Pharmaceutical Synthesis:
(S)-tert-butyl 2-(2-hydroxyethyl)piperazine-1-carboxylate is used as a building block for the synthesis of various pharmaceuticals and fine chemicals. Its unique structure allows it to be a key component in the creation of complex organic molecules for medicinal applications.
Used as a Chiral Auxiliary in Organic Synthesis:
In the field of organic synthesis, (S)-tert-butyl 2-(2-hydroxyethyl)piperazine-1-carboxylate is utilized as a chiral auxiliary. It is employed for its ability to induce asymmetric induction, which is crucial for the production of enantiomerically pure compounds, often necessary for biological activity and selectivity in drug development.
Used in Medicinal Chemistry for Drug Development:
(S)-tert-butyl 2-(2-hydroxyethyl)piperazine-1-carboxylate is applied in medicinal chemistry for the development of new drugs and therapeutic agents. Its potential in this area stems from its capacity to influence the stereochemistry of molecules, which is vital for the efficacy and selectivity of pharmaceutical compounds.
Used in the Development of Asymmetric Catalysis:
(S)-tert-butyl 2-(2-hydroxyethyl)piperazine-1-carboxylate may also be used in the development of asymmetric catalysis techniques, where its chiral properties can be leveraged to produce enantioselective reactions, leading to the synthesis of biologically active molecules with a single enantiomer.
Used in Research and Development of Novel Chemical Entities:
In the research and development sector, (S)-tert-butyl 2-(2-hydroxyethyl)piperazine-1-carboxylate serves as a valuable tool for probing new chemical space and developing novel chemical entities with potential therapeutic benefits.

Check Digit Verification of cas no

The CAS Registry Mumber 169448-17-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,9,4,4 and 8 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 169448-17:
(8*1)+(7*6)+(6*9)+(5*4)+(4*4)+(3*8)+(2*1)+(1*7)=173
173 % 10 = 3
So 169448-17-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H22N2O3/c1-11(2,3)16-10(15)13-6-5-12-8-9(13)4-7-14/h9,12,14H,4-8H2,1-3H3/t9-/m0/s1

169448-17-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (S)-tert-Butyl 2-(2-hydroxyethyl)piperazine-1-carboxylate

1.2 Other means of identification

Product number -
Other names tert-butyl (2S)-2-(2-hydroxyethyl)piperazine-1-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:169448-17-3 SDS

169448-17-3Relevant articles and documents

CYCLIC (AZA)INDOLIZINECARBOXAMIDES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS

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, (2011/02/24)

The present invention relates to cyclic indolizinecarboxamides and azaindolizinecarboxamides of the formulae Ia and Ib, (Ia) (Ib) wherein R, Ra, R10, R20, R30, R40, Y, n, p and q have the meanings ind

Thioproline-containing inhibitors of farnesyl protein transferase

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, (2008/06/13)

Inhibition of farnesyl transferase, which is an enzyme involved in ras oncogene expression, is effected b STR1 its enantiomers, diastereomers, and pharmaceutically acceptable salts and solvates thereof.

2-Substituted piperazines as constrained amino acids. Application to the synthesis of potent, non carboxylic acid inhibitors of farnesyltransferase [1]

Williams,Ciccarone,MacTough,Bock,Conner,Davide,Hamilton,Koblan,Kohl,Kral,Mosser,Omer,Pompliano,Rands,Schaber,Shah,Wilson,Gibbs,Graham,et al.

, p. 1345 - 1348 (2007/10/03)

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