169452-08-8 Usage
Description
1-(4-Fluoro-benzyl)-pyrrolidin-3-ylamine dihydrochloride is a chemical compound belonging to the class of pyrrolidines. It is a dihydrochloride salt form of 1-(4-fluoro-benzyl)-pyrrolidin-3-ylamine, which functions as a selective antagonist for the nociceptin/orphanin FQ (NOP) receptor. 1-(4-FLUORO-BENZYL)-PYRROLIDIN-3-YLAMINE DIHYDROCHLORIDE is significant in research studies, particularly for understanding its potential in pain management and the treatment of various neurological disorders. It serves as a crucial tool in exploring the NOP receptor's role in the human body, with its dihydrochloride form enhancing its stability and suitability for laboratory use.
Uses
Used in Pharmaceutical Research:
1-(4-Fluoro-benzyl)-pyrrolidin-3-ylamine dihydrochloride is used as a research compound for investigating its potential role in pain management. Its interaction with the NOP receptor makes it a valuable asset in understanding and developing treatments for chronic pain conditions.
Used in Neurological Disorder Treatment:
In the field of neuroscience, 1-(4-Fluoro-benzyl)-pyrrolidin-3-ylamine dihydrochloride is used as a research compound to explore its potential in treating neurological disorders. 1-(4-FLUORO-BENZYL)-PYRROLIDIN-3-YLAMINE DIHYDROCHLORIDE's antagonistic properties towards the NOP receptor may provide insights into the development of therapies for conditions such as anxiety, depression, and addiction.
Used in Drug Development:
1-(4-Fluoro-benzyl)-pyrrolidin-3-ylamine dihydrochloride is utilized as a starting point for the development of new drugs targeting the NOP receptor. Its structural properties and antagonistic action can be leveraged to design and synthesize novel compounds with improved pharmacological profiles for various therapeutic applications.
Used in Chemical Synthesis:
In the chemical industry, 1-(4-Fluoro-benzyl)-pyrrolidin-3-ylamine dihydrochloride can be used as a building block or intermediate in the synthesis of more complex molecules with potential applications in various fields, including pharmaceuticals, agrochemicals, and materials science.
Used in Quality Control and Standardization:
1-(4-FLUORO-BENZYL)-PYRROLIDIN-3-YLAMINE DIHYDROCHLORIDE is also employed in quality control processes to ensure the purity and potency of NOP receptor antagonists. It serves as a reference standard for the development and validation of analytical methods and assays used in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 169452-08-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,9,4,5 and 2 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 169452-08:
(8*1)+(7*6)+(6*9)+(5*4)+(4*5)+(3*2)+(2*0)+(1*8)=158
158 % 10 = 8
So 169452-08-8 is a valid CAS Registry Number.
169452-08-8Relevant articles and documents
Triazinone compound and T-type calcium channel inhibitor
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Page/Page column 87; 88, (2016/08/29)
There is provided a novel triazinone compound that has an excellent T-type voltage-dependent calcium channel inhibitory activity and is specifically useful for treatment of pain. A compound of Formula (I), a tautomer of the compound, a pharmaceutically acceptable salt thereof, or a solvate thereof: where each substituent is defined in detail in the description or claims, for example R1 is H or C1-6 alkoxy, etc., each of L1 and L2 is independently a single bond or NR2, etc., L3 is C1-6 alkylene, etc., A is C6-14 aryl or 5 to 10-membered heteroaryl which is optionally substituted, etc., B is C3-11 cycloalkylene, etc., D is C6-14 aryl or 5 to 10-membered heteroaryl which is optionally substituted, etc.
