16947-00-5Relevant academic research and scientific papers
Structure of Phosphorus-Containing Peptide Ligands. X-ray and NMR Structural Study of Free Ligand and Rhodium Complex
Gilbertson, Scott R.,Chen, Guohua,Kao, Jeff,Beatty, Alicia,Campana, Charles F.
, p. 5557 - 5566 (1997)
The structure of a series of phosphorus-containing peptides was studied. The X-ray structure of a phosphorus-containing dodecapeptide is reported. Analysis of the solution structure of similar phosphorus-containing peptides before and after coordination of rhodium is also reported. In both the solid state and in solution, the peptides were found to exist in a mixture of α-helical and 310 helical conformations. Coordination of rhodium to the i, i + 4 orientated phosphine groups appears to alter the conformational preference.
Rapid and efficient synthesis of peptide fragments containing α- aminoisobutyric acid using Fmoc-amino acid chlorides/potassium salt of 1- hydroxybenzotriazole
Suresh Babu, Vommina V.,Gopi, Hosahudya N.
, p. 1049 - 1050 (2007/10/03)
The synthesis of peptides containing multiple Aib residues was accomplished using Fmoc-Aib-Cl in presence of KOBt. As no additional base was added, the duration of coupling reactions could be extended. Thus, the synthesis of the alamethicin 1-4 fragment, Aib-Pro-Aib-Ala, the emerimicin 2- 6 fragment, Aib-Aib-Aib-Val-Gly and the Aib tetramer, Fmoc-(Aib)4-OBzl were accomplished in good yield and purity.
