169532-34-7Relevant academic research and scientific papers
A facile synthesis of vicinal diamines promoted by low-valent niobium: Preparation of chiral octahydrobiisoquinolines and their application to catalytic asymmetric synthesis
Arai, Shigeru,Takita, Satoshi,Nishida, Atsushi
, p. 5262 - 5267 (2007/10/03)
An efficient homocoupling of imines to give vicinal diamines promoted by low-valent niobium, generated by treatment of NbCl5 with zinc powder, is described. The desired products were obtained in good to excellent yields. Dihydroisoquinoline derivatives also gave the coupling products with good diastereoselectivities (D,L/meso). Optical resolution of the racemic octahydrobiisoquinolines was achieved and their complexes with Cu1 used in the catalytic asymmetric oxidative coupling of β-naphthols. Wiley-VCH Verlag GmbH & Co. KGaA, 2005.
Diastereoselective synthesis of piperazines by manganese-mediated reductive cyclization.
Mercer, Gregory J,Sigman, Matthew S
, p. 1591 - 1594 (2007/10/03)
A simple and effective synthesis of trans aryl-substituted piperazines using a Bronsted acid and manganese(0) is described. [reaction: see text]
Synthesis of enantiomerically pure C2-symmetric acyclic and cyclic 1,2-diamines via pinacol coupling of imines
Annunziata, Rita,Benaglia, Maurizio,Caporale, Marinella,Raimondi, Laura
, p. 2727 - 2734 (2007/10/03)
The inter- and intramolecular coupling of imines promoted by samarium diiodide and Lewis acids or by Zn/MsOH was extensively studied. The intramolecular reaction of chiral, enantiomerically pure bis-imines was also considered, and allowed the efficient, s
Intramolecular coupling of chiral diimines using low-valent titanium reagents: Stereoselective synthesis of chiral 3,4-disubstituted-2,5-diazabicyclo[4.4.0]decanes
Periasamy, Mariappan,Srinivas, Gadthula,Suresh, Surisetti
, p. 7123 - 7125 (2007/10/03)
Chiral 3,4-disubstituted-2,5-diazabicyclo[4.4.0]decanes are prepared from (1R,2R)-1,2-diaminocyclohexane derived diimines through intramolecular coupling using low valent titanium reagent systems.
Electroorganic Chemistry. 129. Electroreductive Synthesis of Chiral Piperazines and Enantioselective Addition of Diethylzinc to Aldehydes in the Presence of the Chiral Piperazines
Shono, Tatsuya,Kise, Naoki,Shirakawa, Eiji,Matsumoto, Hideshi,Okazaki, Eiichi
, p. 3063 - 3067 (2007/10/02)
Electroreduction of diimines, prepared from 1,2-diamines and aromatic aldehydes, in acidic media gave intramolecularly coupled products, 2,3-diarylpiperazines, stereoselectively.Chiral tri- and tetrasubstituted piperazines were synthesized effectively fro
