169543-81-1Relevant articles and documents
Chemoselective deprotection of N-Boc group in amino acids and peptides by bismuth(III) trichloride
Navath, Raghavendra S.,Pabbisetty, Kumar B.,Hu, Longqin
, p. 389 - 393 (2006)
Selective deprotection of N-Boc group was achieved in excellent yields using bismuth(III) trichloride in a mixed solvent of acetonitrile and water (50:1, v/v) at 55°C. Acid-labile groups such as Pmc and tert-butyl ester were not affected and no alkylation of tryptophan, methionine, and cysteine residues was observed under the deprotection conditions.