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Usage

Uses

Used in Organic Synthesis:
N-(purine-6-yl)-1-amino-2-propanol is used as a reagent in organic synthesis for the creation of various complex organic molecules. Its unique structure allows it to participate in a range of chemical reactions, making it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used as a Plant Growth Regulator:
In the agricultural industry, N-(purine-6-yl)-1-amino-2-propanol is utilized as a plant growth regulator. It can help control and manipulate the growth and development of plants, potentially leading to increased crop yields and improved resistance to environmental stressors. By modulating plant growth, N-(purine-6-yl)-1-amino-2-propanol can contribute to more efficient and sustainable agricultural practices.

Upstream product

• 87-42-3 6-chloropurine 
• 78-96-6 3-amino-2-propanol 

Relevant academic research and scientific papers

A Study on the Intramolecular Mitsunobu Reaction of N6-(ω-Hydroxyalkyl)adenines

The cyclization of N6-(ω-hydroxyalkyl)adenines with a N6H-group leads to N6,N1 ring closure regardless of the method of the cyclization that was used. Five-membered to eight-membered rings were obtained using NBS/PPh3; however, under Mitsunobu conditions, the eight-membered fused purine was not formed. Surprisingly, the cyclization of N6-methyl-N6-(4-hydroxybutyl)adenine only leads to N6,N7 ring closure using both methods.

Synthesis and Structure Elucidation of (R)-3-(2′-hydroxyprop-1-yl) adenine

(R)-3-(2′-hydroxyprop-1-yl) adenine 4 was obtained by alkylation of adenine 1 with R-propylene carbonate 2 in the presence of pulverized sodium hydroxide in the synthetic process of tenofovir. The elucidation of the structure of 4 was confirmed by single crystal X-ray diffraction and NMR experiments such as 1D 1H, 13C, and DEPT, as well as 2D COSY, HSQC, and HMBC spectra.