16968-09-5 Usage
General Description
1,1',4,4'-Tetrahydro-1,1'-dimethyl-4,4'-bipyridine, also known as Mecamylamine, is a quaternary ammonium compound and a nicotinic receptor antagonist. It is a potent, non-competitive inhibitor of the nicotinic acetylcholine receptors in the autonomic ganglia and at the neuromuscular junction. Mecamylamine is widely used as a research tool in studies of nicotine addiction and as an investigational drug for various psychiatric and neurological disorders. It has been shown to be effective in reducing nicotine withdrawal symptoms and cravings. Mecamylamine is also being studied for its potential use in treating conditions such as depression, ADHD, and Tourette's syndrome. However, it has been associated with various side effects, including dizziness, headaches, and gastrointestinal disturbances.
Check Digit Verification of cas no
The CAS Registry Mumber 16968-09-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,9,6 and 8 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 16968-09:
(7*1)+(6*6)+(5*9)+(4*6)+(3*8)+(2*0)+(1*9)=145
145 % 10 = 5
So 16968-09-5 is a valid CAS Registry Number.
16968-09-5Relevant articles and documents
Photolytic Generation and the Subsequent Dimerization of 4-Alkyl-1-methylpyridinyl Radicals in Solution as Studied by Steady-state and Kinetic ESR Spectroscopy
Akiyama, Kimio,Ishii, Toru,Tero-Kubota, Shozo,Ikegami, Yusaku
, p. 3535 - 3539 (1985)
1-Methylpyridinyl and 4-alkyl-1-methylpyridinyl (alkyl=methyl, ethyl, isopropyl, and t-butyl) radicals were generated photolytically from their dimers in solution.Hyperfine splitting constants for these radicals were assigned and the temperature dependence was discussed.Absolute dimerization rates of these radicals in the range of -50 - -100 deg C were determined by analyzing the ESR signal decay during the dark period.A nearly constant activation energy of dimerization was observed for five radicals, while the frequency factor decreased with the bulkiness of 4-substituent, which are discussed in terms of the steric hindrance for the dimerization.
