16974-42-8

Basic information

• Product Name: deoxysotalol
• Synonyms: deoxysotalol
• CAS NO: 16974-42-8
• Molecular Formula: C12H20N2O2S
• Molecular Weight: 256.3644
• Product Categories: Amines, Aromatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
• Mol File: 16974-42-8.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 381.9°Cat760mmHg
• Flash Point: 184.8°C
• Appearance: /
• Density: 1.157g/cm³
• Vapor Pressure: 4.9E-06mmHg at 25°C
• Refractive Index: 1.55
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility: DMSO (Slightly, Heated), Methanol (Slightly)
• PKA: 8.61±0.10(Predicted)
• CAS DataBase Reference: deoxysotalol(CAS DataBase Reference)
• NIST Chemistry Reference: deoxysotalol(16974-42-8)
• EPA Substance Registry System: deoxysotalol(16974-42-8)

Safety Data

• Hazardous Substances Data: 16974-42-8(Hazardous Substances Data)

Usage

Uses

Deoxysotalol is the metabolite of Sotalol (S677300), a potent α-adrenergic receptor antagonist and A class III antiarrythmic. Several studies have examined deoxysotalol on its effects on prostaglandin (PGF2a and 15-methyl PGF2α)-evoked contraction using isolated rat uterus and also in potentiating the contractile effects of Oxytocin (O878500).

InChI:InChI=1/C12H20N2O2S/c1-10(2)13-9-8-11-4-6-12(7-5-11)14-17(3,15)16/h4-7,10,13-14H,8-9H2,1-3H3

Related news

Potentiating effect of (+)-sotalol and deoxysotalol (cas 16974-42-8) on prostaglandin-evoked contractions of the isolated rat uterus08/05/2019

The effect of (+)-sotalol and deoxysotalol on prostaglandin (PGF2a and 15-methyl PGF2α)-evoked contractions was studied using the isolated rat uterus. After control responses to prostaglandins had been obtained the uterus was exposed to the nutrient fluid containing 10 μg/ml of (+)-sotalol, de...detailed