16975-92-1Relevant academic research and scientific papers
Retrodihydrochalcones in Sorghum species: Key intermediates in the biosynthesis of 3-deoxyanthocyanidins?
Khalil, Ali,Baltenweck-Guyot, Raymonde,Ocampo-Torres, Rubén,Albrecht, Pierre
, p. 174 - 176 (2012)
Two new open chain flavonoids were isolated from the butanediol/ethanol extract of Sorghum bicolor (L.) Moench leaf sheaths by fractionation and purification processes. This work led to the structural characterization of the 3-(2,4,6-trihydroxyphenyl)-1-(
Method for semi-synthesizing 3-deoxyanthocyanidin from 5-OH-7-O-substituted flavanone
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Paragraph 0024, (2016/11/28)
The invention relates to a method for semi-synthesizing 5-OH-7-O-substituted-3-deoxyanthocyanidin from 5-OH-7-O-substituted flavanone, and relates to the fields of chemistry and pharmacy, food and cosmetics. According to the invention, 5-OH-7-O-substituted flavanone is reduced into 5-OH-7-O-substituted flavan-4-ol with reducing agents such as potassium borohydride; direct acid dehydration is carried out, such that a 5-OH-7-O-substituted flavan-4-carbonium ionic compound is produced; water is removed, and iodine-pyridine solvent dehydrogenation is carried out, such that 5-OH-7-O-substituted-3-deoxyanthocyanidin is produced. The 5-OH-7-O-substituted-3-deoxyanthocyanidin is subjected to macroporous absorption resin enrichment, and harmful impurities such as pyridine are removed; and ethanol elution and reduced-pressure recovery are carried out, such that the final product is obtained. According to the invention, multiple reaction steps are integrated into a one-step reaction; operation is simple; and yield is relatively high. The method is suitable for industrial productions. With the method, flavanone glycosides such as hesperidin and naringin can be prepared into 3-deoxyanthocyanidin with good water solubility and oxidation resistance.
BIOSYNTHESIS OF 3-DEOXYANTHOCYANINS WITH FLOWER EXTRACTS FROM SINNINGIA CARDINALIS
Stich, K.,Forkmann, G.
, p. 785 - 790 (2007/10/02)
Soluble enzyme preparations from flowers of Sinningia cardinalis catalyse a NADPH-dependent reduction of (2S)-naringenin to the respective flavan-4-ol apiforol (leucoapigeninidin) and of (2S)-eriodictyol to luteoforol (leucoluteolinidin).NADPH can be substituted to a great extent by NADH.The reaction has a pH optimum around 6.0 and is inhibited about 50percent by p-chloromercuribenzoate.The significance of the reaction for the 3-deoxyanthocyanin pathway and the relationship of flavanone 4-reductase and dihydroflavonol 4-reductase, which was also found to be active in the flower extracts, is discussed.Key Word Index-Sinningia cardinalis; 3-deoxyanthocyanidin biosynthesis; flavanone 4-reductase; flavan-4-ol.
