169750-42-9

Basic information

• Product Name: Carbamic acid, [(3R,4S)-4-fluoro-3-pyrrolidinyl]-, 1,1-dimethylethyl ester, rel-
• Synonyms: Carbamic acid, [(3R,4S)-4-fluoro-3-pyrrolidinyl]-, 1,1-dimethylethyl ester, rel-;cis-(3-Boc-aMino)-4-fluoropyrrolidine;tert-Butyl (cis-4-fluoropyrrolidin-3-yl)carbamate;tert-butyl N-[cis-4-fluoropyrrolidin-3-yl]carbamate
• CAS NO: 169750-42-9
• Molecular Formula: C9H17FN2O2
• Molecular Weight: 204.25
• Product Categories: N-BOC
• Mol File: 169750-42-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 295.3±40.0 °C(Predicted)
• Appearance: /
• Density: 1.10±0.1 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 11.18±0.40(Predicted)
• CAS DataBase Reference: Carbamic acid, [(3R,4S)-4-fluoro-3-pyrrolidinyl]-, 1,1-dimethylethyl ester, rel-(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(3R,4S)-4-fluoro-3-pyrrolidinyl]-, 1,1-dimethylethyl ester, rel-(169750-42-9)
• EPA Substance Registry System: Carbamic acid, [(3R,4S)-4-fluoro-3-pyrrolidinyl]-, 1,1-dimethylethyl ester, rel-(169750-42-9)

Safety Data

• Hazardous Substances Data: 169750-42-9(Hazardous Substances Data)

Usage

General Description

Carbamic acid, [(3R,4S)-4-fluoro-3-pyrrolidinyl]-, 1,1-dimethylethyl ester, rel- is a chemical compound with the molecular formula C10H18FN3O2. Carbamic acid, [(3R,4S)-4-fluoro-3-pyrrolidinyl]-, 1,1-dimethylethyl ester, rel- is commonly used in the pharmaceutical industry as a precursor in the synthesis of various drugs. It is a tert-butyl ester of a fluoropyrrolidinyl carbamic acid, which forms a key structural component in many pharmaceutical compounds. This chemical is considered to be of high importance in drug development and research due to its versatile role in creating biologically active molecules.

Relevant articles and documents

Asymmetric Synthesis of cis -(S, R)-3-Amino-4-fluoro-1-methylpyrrolidine

The development of the stereoselective synthesis of cis -(S, R)-3-amino-4-fluoro-1-methylpyrrolidine is described starting from chiral, non-racemic 1-[(3 S,4 S)-3-azido-4-hydroxypyrrolidin-1-yl]-2,2,2-trifluoroethan-1-one. Two sets of deoxyfluorination co

PURINE DERIVATIVES

The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein Q, G, ring A, ring B, R1, R2, R3, R4, R5, R5a, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, R18, R19, R20, R21, R22, R23, R24, and m are defined herein. The novel purine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. Additional embodiments relate to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.