16976-09-3

Basic information

• Product Name: 9-[2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl]-3,9-dihydro-6H-purine-6-thione
• Synonyms: 6H-Purine-6-thione, 9-(2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl)-1,9-dihydro-, (1alpha,2alpha,3beta,4alpha)-; 6H-Purine-6-thione, 9-(2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl)-1,9-dihydro-, (1alpha,2beta,3alpha,4alpha)-; 6H-Purine-6-thione, 9-[2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl]-1,9-dihydro-, (1.alpha.,2.beta.,3.alpha.,4.alpha.)-; 6H-Purine-6-thione, 9-[2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl]-1,9-dihydro-, (1a,2a,3b,4a)-
• CAS NO: 16976-09-3
• Molecular Formula: C₁₁H₁₄N₄O₃S
• Molecular Weight: 282.3189
• Mol File: 16976-09-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 631.5°C at 760 mmHg
• Flash Point: 335.7°C
• Density: 1.88g/cm³
• Vapor Pressure: 8.12E-17mmHg at 25°C
• Refractive Index: 1.88
• CAS DataBase Reference: 9-[2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl]-3,9-dihydro-6H-purine-6-thione(CAS DataBase Reference)
• NIST Chemistry Reference: 9-[2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl]-3,9-dihydro-6H-purine-6-thione(16976-09-3)
• EPA Substance Registry System: 9-[2,3-dihydroxy-4-(hydroxymethyl)cyclopentyl]-3,9-dihydro-6H-purine-6-thione(16976-09-3)

Safety Data

• Hazardous Substances Data: 16976-09-3(Hazardous Substances Data)

Downstream Products

• 1233860-48-4 (1'R,2'S,3'R,4'R)-1-[2,3-dihydroxy-4-(hydroxymethyl)-cyclopentan-1-yl]-6-(2-fluorobenzyl-thio)purine 
• 1233860-59-7 (1'R,2'S,3'R,4'R)-1-[2,3-dihydroxy-4-(hydroxymethyl)cyclopentan-1-yl]-6-(4-methoxy-carbonylbenzylthio)purine 
• 1233860-53-1 (1'R,2'S,3'R,4'R)-1-[2,3-dihydroxy-4-(hydroxymethyl)cyclopentan-1-yl]-6-(3-methylbenzyl-thio)purine 
• 1233860-67-7 (1'R,2'S,3'R,4'R)-1-[2,3-dihydroxy-4-(hydroxymethyl)cyclopentan-1-yl]-6-(2,4,6-trimethyl-benzylthio)purine 
• 1233860-66-6 (1'R,2'S,3'R,4'R)-1-[2,3-dihydroxy-4-(hydroxymethyl)cyclopentan-1-yl]-6-(2-chloro-6-fluorobenzylthio)purine 
• 1233860-62-2 (1'R,2'S,3'R,4'R)-1-[2,3-dihydroxy-4-(hydroxymethyl)cyclopentan-1-yl]-6-(4-trifluoro-methoxybenzylthio)purine 
• 1233860-47-3 (1'R,2'S,3'R,4'R)-1-[2,3-dihydroxy-4-(hydroxymethyl)cyclopentan-1-yl]-6-benzylthiopurine 
• 1233860-49-5 (1'R,2'S,3'R,4'R)-1-[2,3-dihydroxy-4-(hydroxymethyl)cyclopentan-1-yl]-6-(2-chlorobenzyl-thio)purine 
• 1233860-63-3 (1'R,2'S,3'R,4'R)-1-[2,3-dihydroxy-4-(hydroxymethyl)cyclopentan-1-yl]-6-(4-methoxy-benzylthio)purine 
• 1233860-60-0 (1'R,2'S,3'R,4'R)-1-[2,3-dihydroxy-4-(hydroxymethyl)cyclopentan-1-yl]-6-(4-methylbenzyl-thio)purine 
• 1233860-55-3 (1'R,2'S,3'R,4'R)-1-[2,3-dihydroxy-4-(hydroxymethyl)cyclopentan-1-yl]-6-(4-chlorobenzyl-thio)purine 
• 1233860-56-4 (1'R,2'S,3'R,4'R)-1-[2,3-dihydroxy-4-(hydroxymethyl)cyclopentan-1-yl]-6-(4-bromobenzyl-thio)purine 
• 1233860-50-8 (1'R,2'S,3'R,4'R)-1-[2,3-dihydroxy-4-(hydroxymethyl)cyclopentan-1-yl]-6-(2-methylbenzyl-thio)purine 
• 1233860-54-2 (1'R,2'S,3'R,4'R)-1-[2,3-dihydroxy-4-(hydroxymethyl)cyclopentan-1-yl]-6-(4-fluorobenzyl-thio)purine 

Relevant articles and documents

Structure-activity relationships of carbocyclic 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase

Carbocyclic 6-benzylthioinosine analogues were synthesized and evaluated for their binding affinity against Toxoplasma gondii adenosine kinase [EC.2.7.1.20]. Various substituents on the aromatic ring of the 6-benzylthio group resulted in increased binding