169870-76-2Relevant academic research and scientific papers
Dispiroketals in synthesis (Part 16): Functionalised dispiroketals as new chiral auxiliaries; the synthesis of dihydroxylated dispiroketals in optically pure form and their application as bifunctional , C2-symmetrical, chiral auxiliaries for highly stereoselective Michael additions
Bezuidenhoudt, Barend C. B.,Castle, Grant H.,Innes, Jean E.,Ley, Steven V.
, p. 184 - 194 (2007/10/02)
A range of rigid, architecturally complex diols derived from dispiroketals have been synthesised.A bifunctional, C2-symmetrical, chiral auxiliary derived from these dihydroxylated dispiroketals has been used to induce a high degree of asymmetry in Michael additions of cuprates to a variety of di-α,β-unsaturated ester systems.
Dispiroketals in Synthesis (Part 14): Functionalised Dispiroketals as New Chiral Auxiliaries; Highly Stereoselective Michael Additions to a Bifunctional, C2-Symmetrical Chiral Auxiliary.
Castle, Grant H.,Ley, Steven V.
, p. 7455 - 7458 (2007/10/02)
A bifunctional, C2-symmetrical chiral auxiliary derived from dihydroxylated dispiroketals has been used to induce a high degree of asymmetry in Michael additions of cuprates to a variety of di-α,β-unsaturated ester systems.
