169873-64-7

Upstream product

• 20341-92-8 4-Bromo-3-oxo-2-(triphenyl-λ⁵-phosphanylidene)-butyric acid ethyl ester 
• 95260-60-9 (2S,4S)-benzyl 4-benzyl-5-oxo-2-phenyloxazolidine-3-carboxylate 
• 169787-81-9 (2S,4R)-4-Benzhydryloxycarbonylmethyl-4-benzyl-5-oxo-2-phenyl-oxazolidine-3-carboxylic acid benzyl ester 
• 169787-82-0 (2'S,4'R)-4'-benzyl-3'-benzyloxycarbonyl-5'-oxo-2'-phenyloxazolidin-4'-ylacetic acid 
• 169787-90-0 (2'S,4'R)-4'-benzyl-3'-benzyloxycarbonyl-5'-oxo-2'-phenyloxazolidin-4'-ylacetyl chloride 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 

Downstream Products

• 169787-98-8 (4'R,E)-(-)-ethyl (4'-benzyl-4'-benzyloxycarbonylamino-5'-oxotetrahydrofuran-2'-ylidene)acetate 
• 169787-87-5 {(R)-3-Benzyl-3-benzyloxycarbonylamino-5-[1-ethoxycarbonyl-meth-(E)-ylidene]-2-oxo-pyrrolidin-1-yl}-acetic acid 
• 169787-94-4 (4'R,E)-(-)-ethyl (4'-benzyl-4'-benzyloxycarbonylamino-5-oxotetrahydrofuran-2'-ylidene)bromoacetate 
• 169787-91-1 (5R)-ethyl hydrogen 5-benzyl-5-benzyloxycarbonylamino-3-oxo-2-(triphenylphosphoranylidene)hexanedioate 

Relevant academic research and scientific papers

Synthesis of Phenylalanine-based Cyclic Acylated Enamino Ester Dipeptide Analogues: Inhibitors of α-Chymotrypsin. X-Ray Molecular Structure of (2'S,4'R)-4'-Benzyl-3'-benzyloxycarbonyl-5'-oxo-2'-phenyloxazolidin-4'-ylacetic Acid

Alkylation of the (S)-phenylalanine-derived syn-oxazolidinone 8 with BrCH2CO2CHPh2 gave compound 9, a key precursor to the β-keto ester 11 and the keto acid phosphorane 17.Compound 17 gave the enolactone 24 on heating and the bromo enolactone 19 and 20 on