169878-79-9Relevant articles and documents
Structure-activity study of novel tricyclic benzazepine arginine vasopressin antagonists
Sum, Fuk-Wah,Dusza, John,Delos Santos, Efren,Grosu, George,Reich, Marvin,Du, Xumei,Albright, J. Donald,Chan, Peter,Coupet, Joseph,Ru, Xun,Mazandarani, Hossein,Saunders, Trina
, p. 2195 - 2198 (2003)
Novel tricyclic benzazepine derivatives were synthesized as arginine vasopressin (AVP) antagonists. Several tricyclic compounds showed potent antagonistic activity in rat AVP receptors V1a and V2. Derivatives containing pyrrolo-tricy