169886-85-5

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 169886-81-1 5'-O-4,4'-dimethoxytrityl-6-methyluridine 
• 16710-13-7 6-methyluridine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 

Downstream Products

• 169886-86-6 (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(6-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite 

Relevant academic research and scientific papers

Synthesis and properties of uniquely modified oligoribonucleotides: Yeast tRNA(Phe) fragments with 6-methyluridine and 5,6-dimethyluridine at site-specific positions

The phosphoramidites of 6-methyluridine and 5,6-dimethyluridine were synthesized and the modified uridines site-selectively incorporated into heptadecamers corresponding in sequence to the yeast tRNA(Phe) anticodon and TΨC domains. The oligoribonucleotide

Synthesis of 6-aza- and 6-methyl-pyrimidine ribonucleoside phosphoramidites and their incorporation in hammerhead ribozymes

The synthesis of phosphoramidites of 6-modified pyrimidine ribonucleosides and their incorporation into hammerhead ribozymes and influence on nuclease stability and catalytic activity is described.