169954-72-7

Upstream product

• 169954-71-6 [1,1-Dimethyl-2-(3-{(R)-2-oxo-1-[2'-(1-trityl-1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl}-ureido)-ethyl]-carbamic acid tert-butyl ester 
• 169953-04-2 1-(2-Amino-2-methyl-propyl)-3-{(R)-2-oxo-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl}-urea 
• 169954-69-2 {1,1-Dimethyl-2-[3-((R)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)-ureido]-ethyl}-carbamic acid tert-butyl ester 
• 137036-55-6 (R)-3-amino-2,3,4,5-tetrahydro-1H-[1]-benzazepin-2-one 
• 124750-51-2 N-(triephenylmethyl)-5-<4'-(bromomethyl)-biphenyl-2-yl>tetrazole 
• 53346-05-7 (R)-2-benzyloxypropanal 

Relevant academic research and scientific papers

Benzolactam growth hormone secretagogues: Replacement of the C-3 amide bond in L-692,429

The synthesis and structure-activity relationships of various C-3 amide bond modifications in the novel nonpeptidyl growth hormone secretagogue L-692,429 are described. Several C-3 amide surrogates were prepared and the urea moiety was found to exhibit growth hormone releasing activity similar to that observed with L-692,429.