170006-72-1 Usage
Uses
N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine Trifluoroacetate Salt is a useful intermediate.
Biochem/physiol Actions
FTI-276 is a highly potent RasCAAX peptidomimetic. FTI-276 antagonizes both H and K-Ras oncogenic signaling. It is an inhibitor of farnesyltransferase (Ftase) in vitro with an IC50 of 500 pM and is an anti-cancer agent.
Check Digit Verification of cas no
The CAS Registry Mumber 170006-72-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,0,0,0 and 6 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 170006-72:
(8*1)+(7*7)+(6*0)+(5*0)+(4*0)+(3*6)+(2*7)+(1*2)=91
91 % 10 = 1
So 170006-72-1 is a valid CAS Registry Number.
170006-72-1Relevant articles and documents
Inhibitors of prenyl transferases
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, (2008/06/13)
Compounds which inhibit prenyl transferases, particularly farnysyltransferase and geranylgeranyl transferase I, processes for preparing the compounds, pharmaceutical compositions containing the compounds, and methods of use.
