170031-71-7Relevant academic research and scientific papers
Synthesis and anticancer and anti-HIV testing of some pyrazino[1,2-a]benzimidazole derivatives
Demirayak, Seref,Abu Mohsen, Usama,Cagri Karaburun, Ahmet
, p. 255 - 260 (2002)
In this study, some 1-methylene-2,3-diaryl-1,2-dihydropyrazino[1,2-a]benzimidazole and some 1-(2-arylvinyl)-3-arylpyrazino[1,2-a]benzimidazole derivatives were synthesised. The structure elucidation of the compounds was performed by IR, 1H-NMR and MASS spectroscopic data and elemental analyses results. Anticancer and anti-HIV activities of the compounds were examined, however no anti-HIV activity was seen; highly notable anticancer activity was obtained. It was also observed that the compounds were more potent against leukaemia cell lines.
Synthesis of some pyrido- and pyrazino-benzimidazole derivatives and their antifungal activity
Demirayak,Guven
, p. 527 - 529 (2007/10/02)
Some 2-aryl-4-hydroxypyrido[1,2-a]benzimidazole and 1-substituted 3-arylpyrazino-[1,2-a]benzimidazole derivatives were synthesized using 1-(2-arylethan-2-on)2-acylbenzimidazole derivatives as starting materials. Antifungal activities of the compounds obtained were examined in vitro.
