170078-65-6 Usage
Uses
Used in Pharmaceutical Industry:
2,3-DI-O-BENZYL-4,6-O-ETHYLIDENE-BETA-D-GLUCOPYRANOSE is used as a precursor for the synthesis of bioactive compounds and natural products, contributing to the development of new pharmaceuticals with potential therapeutic applications.
Used in Agrochemical Industry:
DOBEG is utilized as a starting material for the synthesis of agrochemicals, including pesticides and other compounds that can enhance crop protection and yield.
Used in Material Science:
2,3-DI-O-BENZYL-4,6-O-ETHYLIDENE-BETA-D-GLUCOPYRANOSE is employed in the development of new materials, leveraging its unique chemical structure to create innovative materials with specific properties for various applications.
Used in Drug Delivery Systems:
DOBEG has been studied for its role in the development of drug delivery systems, potentially improving the efficiency and targeting of therapeutic agents in medical treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 170078-65-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,0,0,7 and 8 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 170078-65:
(8*1)+(7*7)+(6*0)+(5*0)+(4*7)+(3*8)+(2*6)+(1*5)=126
126 % 10 = 6
So 170078-65-6 is a valid CAS Registry Number.
170078-65-6Relevant articles and documents
Efficient synthesis of the anticancer drug etoposide 4′-phosphate: Use of benzylic ether-protecting groups on the carbohydrate segment
Silverberg, Lee J.,Dillon, John L.,Vemishetti, Purushotham,Sleezer, Paul D.,Discordia, Robert P.,Hartung, Kerry B.,Gao, Qi
, p. 34 - 42 (2013/09/07)
The prodrug etoposide phosphate 2 is synthesized efficiently in three steps in 54.6% overall yield from 4′-demethylepipodophyllotoxin 3. The strategy pursued in the synthesis of 2 places the phosphate on 3 prior to coupling with the sugar and employs benzyl ether-protecting groups on both the phosphate and the sugar, allowing easy removal in one step. The importance of solvent, steric effects, and electronic effects in the coupling reaction is demonstrated. Two features of the synthesis are an unusual thermal anomerization of the carbohydrate component 5a and completely diastereoselective, one-pot crystallization of the coupled product 6a-β. The process has been demonstrated on multi-kilogram scale.
Epipodophyllotoxin glycosides
-
, (2008/06/13)
The present invention relates to novel antitumor compounds which are 4'-demethylepipodophylloxtoxin derivatives. More particularly, the novel compounds are 4'-demethylepipodophyllotoxin allopyranosides, allofuranosides, and mannopyranosides.
