170079-57-9Relevant academic research and scientific papers
A Convenient Asymmetric Synthesis of Thalidomide
Robin, Sylvie,Zhu, Jiarong,Galons, Herve,Pham-Huy, Chuong,Claude, Jean Roger,et al.
, p. 1249 - 1252 (2007/10/02)
Benzyloxyamine reacted with BOC-glutamic-α-phenyl ester in the presence of carbodiimide to give BOC-amino-N-benzyloxypiperidinedione.Deprotection of the amino group followed by phthaloylation led to N-benzyloxythalidomide which was then converted into thalidomide.
