170115-18-1

Basic information

• Product Name: BETA-OXO-2-FURANPROPANOIC ACID 1,1-DIMETHYLETHYL ESTER
• Synonyms: BETA-OXO-2-FURANPROPANOIC ACID 1,1-DIMETHYLETHYL ESTER;b-Oxo-2-furanpropanoic acid tert-butyl ester
• CAS NO: 170115-18-1
• Molecular Formula: C11H14O4
• Molecular Weight: 210.228
• Mol File: 170115-18-1.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BETA-OXO-2-FURANPROPANOIC ACID 1,1-DIMETHYLETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: BETA-OXO-2-FURANPROPANOIC ACID 1,1-DIMETHYLETHYL ESTER(170115-18-1)
• EPA Substance Registry System: BETA-OXO-2-FURANPROPANOIC ACID 1,1-DIMETHYLETHYL ESTER(170115-18-1)

Safety Data

• Hazardous Substances Data: 170115-18-1(Hazardous Substances Data)

Upstream product

• 98-01-1 furfural 
• 540-88-5 acetic acid tert-butyl ester 
• 95091-92-2 N-methoxy-N-methyl-2-furancarboxamide 
• 527-69-5 2-furancarbonyl chloride 
• 88-14-2 2-furanoic acid 

Downstream Products

• 1454283-82-9 5-tert-butyl 2-ethyl 6-(furan-2-yl)-4-phenylpyridine-2,5-dicarboxylate 
• 1641546-31-7 C₂₀H₂₀O₄ 
• 1627205-42-8 3-furan-2-yl-2-(3-phenylprop-2-ynyl)-2H-azirine-2-carboxylic acid tert-butyl ester 
• 1627205-63-3 2-furan-2-yl-6-phenylnicotinic acid tert-butyl ester 
• 1641546-39-5 C₂₀H₂₁NO₄ 
• 10564-00-8 4-(furan-2-yl)-4-oxobutanoic acid 

Relevant articles and documents

Synthesis and antibacterial activities of cadiolides A, B and C and analogues

The one-pot multicomponent synthesis of natural butenolides named cadiolides A, B, C and analogues has been realized. The antibacterial structure activity relationship shows that the presence of phenolic hydroxyl groups and the number and position of bromine atoms on the different aromatic rings are important features for antibacterial activity, besides it was demonstrated the tolerance of both benzene and furan ring at position 3 of the butenolide nucleus. Furthermore, none of the most relevant antibacterial compounds showed any cytotoxicity in freshly isolated human neutrophils.

Versatile synthesis of acylfuranones by reaction of acylketenes with α-hydroxy ketones: Application to the one-step multicomponent synthesis of cadiolide B and its analogues

Functionalized acylfuranones have been prepared in a one-step procedure by thermal fragmentation of the corresponding dioxinones in the presence of hydroxy ketones in basic conditions. Multicomponent reactions also occur on addition of an aldehyde as a third reaction partner resulting in an expeditious access to cadiolide B and its analogues. A new method for the synthesis of acylfuranones is described based on the fragmentation of dioxinones to acylketenes followed by trapping with hydroxy ketones. Addition of an aldehyde as a third reaction partner leads to a supplementary aldolization/crotonization sequence resulting in an expeditious synthesis of cadiolide B and its analogues. Copyright

Oxyiminoalkanoic acid derivatives with hypoglycemic and hypolipidemic activity

This invention provides a novel oxyiminoalkanoic acid derivative which has excellent hypoglycemic and hypolipidemic actions and which is used for the treatment of diabetes mellitus, hyperlipemia, insulin insensitivity, insulin resistance and impaired glucose tolerance.