170243-08-0Relevant academic research and scientific papers
Thiopyranoindoles as Inhibitors of 5-Lipoxygenase, 5-Lipoxygenase-Activating Protein, and Leukotriene C4 Synthase
Hutchinson, John H.,Charleson, Stella,Evans, Jilly F.,Falgueyret, Jean-Pierre,Hoogsteen, Karst,et al.
, p. 4538 - 4547 (2007/10/03)
The attachment of an arylacetic or benzoic acid moiety to the thiopyranoindole nucleus results in compounds which are highly potent and selective 5-lipoxygenase (5-LO) inhibitors.These compounds are structurally simpler than previous compounds
