170244-03-8Relevant academic research and scientific papers
Synthesis and activity of phenyl derivatives containing 5,6-dimethyl-thieno [2,3-d] pyrimidin-4(1H)-one or 4H-pyrimido [5,4-b] indol-4-one heterocyclic system as potential non steroidal anti-inflammatory drugs
Santagati, Andrea,Granata, Giuseppe,Santagati, Maria,Cutuli, Vincenza,Mangano, Nunzio Guido,Caruso, Antonina
, p. 448 - 454 (2007/10/03)
The synthesis, the analgesic and anti-inflammatory activities of two series of phenyl derivatives containing 5,6-dimethyl-thieno[2,3-d]pyrimidin-4(1H)-one and 4H-pyrimido[5,4-b]indol-4-one system, respectively, are reported. Two of these derivatives, 6A and 9B, showed interesting activities. The results of the pharmacological assays are discussed.
Synthesis and pharmacological properties of thieno[2',3':4,5]pyrimido [2,1-b][1,3,4]thiadiazine derivatives
Santagati,Modica,Santagati,Cutuli,Amore,Caruso
, p. 605 - 609 (2007/10/03)
A new series of 2-substituted-7,8-dimethyl-3H,9H-thieno[2',3':4,5]pyrimido[2,1b][1,3,4 ]thiadiazin-9-ones 5a-d and 6a,b was synthesized through the hydrazinium(1+) salt of 3-amino-2,3-dihydro-5,6-dimethyl-2-thioxo-thieno[2,3-d]pyrimidin-4(1H- one, 2. Thes
