17027-93-9Relevant academic research and scientific papers
New furin inhibitors based on weakly basic amidinohydrazones
Sielaff, Frank,Than, Manuel E.,Bevec, Dorian,Lindberg, Iris,Steinmetzer, Torsten
body text, p. 836 - 840 (2011/02/27)
A novel series of amidinohydrazone-derived furin inhibitors was prepared; the most potent compounds 17 and 21 inhibit furin with Ki values of 0.46 and 0.59 μM, respectively. In contrast to inhibitor 17, which still contains a guanidino residue,
