17036-77-0

Upstream product

• 80-59-1 Tiglic acid 
• 74806-83-0 (E)-4-Benzenesulfonyl-2-benzoylamino-2-methyl-but-3-enoic acid methyl ester 
• 74761-79-8 4-((E)-2-Benzenesulfonyl-vinyl)-4-methyl-2-phenyl-4H-oxazol-5-one 
• 353456-94-7 N-(1-hydroxymethyl-1-methyl-allyl)-4-methyl-benzenesulfonamide 
• 114978-89-1 4-<(tetrahydro-2H-pyran-2-yl)oxy>-3-methyl-2E-buten-1-ol 
• 100450-08-6 α-vinylalaninol 
• 882048-51-3 N-(p-methoxyphenyl)-O-(tetrahydro-2'H-pyran-2'-yl)-N-trifluoroacetyl-α-vinylalaninol 
• 882048-75-1 N-(9-fluorenylmethoxycarbonyl)-α-vinylalaninol 
• 882048-62-6 N-(p-methoxyphenyl)-O-(tetrahydro-2'H-pyran-2'-yl)-α-vinylalaninol 
• 882048-79-5 N-(9-fluorenylmethoxycarbonyl)-α-vinylalanine 
• 353456-95-8 2-methyl-2-(toluene-4-sulfonylamino)-but-3-enoic acid 
• 74761-87-8 2-Benzoylamino-2-methyl-but-3-enoic acid 
• 74761-84-5 (+/-)-N-benzoyl-α-vunylalanine methyl ester 
• 16820-10-3 5-methyl-5-vinyl-imidazolidine-2,4-dione 

Downstream Products

• 157794-59-7 (+/-)-Benzyl N-(benzyloxycarbonyl)-α-vinylalaninate 

Relevant academic research and scientific papers

A formal [3,3]-sigmatropic rearrangement route to quaternary α-vinyl amino acids: Use of allylic N-PMP trifluoroacetimidates

Pd(II)-mediated rearrangement of allylic N-PMP (p-methoxyphenyl) trifluoroacetimidates provides the first formal sigmatropic route to quaternary, α-vinylic amino acids, potential suicide substrates for PLP enzymes. The amino acid side chains enter via tra

Aziridination of 5-methyl-4H-1,3-dioxins by N-tosyliminophenyliodinane: A one-step procedure for the synthesis of α-methylserinal derivatives

The methyl analogue of Garner's aldehyde, N-tosyl-4-methyl-N, O-isobutyrylideneserinal, has been prepared in a one-step reaction by CuClO4-catalyzed aziridination of 2-isopropyl-5-methyl-4 H-1,3-dioxin with N-tosyliminophenyliodinane and transformed into α-methylserine derivatives, e.g. α-vinylalanine.

Formal α-Vinylation of Amino Acids. Use of a New Benzeneselenolate Equivalent

A new synthetic approach to the formal α-vinylation of α-amino acids is described, in which the readily available electrophile, ethylene oxide, serves as the vinyl cation equivalent.N-Benzoyl α-amino esters bearing appropriate side-chain protecting groups

Polyenolates of unsaturated carboxylic acids in synthesis. Synthesis of unsaturated α-amino acids and γ-hydrazino acids

Regioselective reaction of lithium diene- and triene-diolates 1 and 2 with o-diphenylphosphinyl hydroxylamine affords unsaturated α-amino acids 3 and 4. Addition to DEAD leads selectively to γ-hydrazino unsaturated acids 5 and 6.