1704-69-4

Usage

Uses

Used in Specialty Chemicals Production:
Morpholine, 2,2,3,3,5,5,6,6-octafluoro-4-(heptafluoropropyl)is used as a key ingredient in the production of specialty chemicals, such as pharmaceuticals and polymers. Its unique properties make it suitable for creating high-performance materials with specific characteristics.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Morpholine, 2,2,3,3,5,5,6,6-octafluoro-4-(heptafluoropropyl)is used as an intermediate in the synthesis of various drugs. Its ability to form stable compounds with other molecules contributes to the development of effective medications.
Used in Surfactant Manufacturing:
Morpholine, 2,2,3,3,5,5,6,6-octafluoro-4-(heptafluoropropyl)is utilized in the manufacturing of surfactants, which are essential components in various consumer products, such as detergents, shampoos, and cleaning agents. Its properties help improve the performance and stability of these products.
Used in Resin and Coating Production:
In the production of resins and coatings, Morpholine, 2,2,3,3,5,5,6,6-octafluoro-4-(heptafluoropropyl)is used as an additive to enhance the properties of the final products. Its incorporation can improve the durability, resistance, and overall performance of resins and coatings.
Used in Safety and Handling:
Due to its low toxicity, Morpholine, 2,2,3,3,5,5,6,6-octafluoro-4-(heptafluoropropyl)is considered safe for handling when proper precautions are taken. This makes it a preferred choice in industries where worker safety and environmental concerns are paramount.

Upstream product

• 59352-41-9 2-chloro-3-morpholinopropene 
• 20120-26-7 (2-methyl-3-morpholin-4-yl)propionic acid methyl ester 
• 32418-63-6 ethyl 2-morpholinobutyrate 
• 5471-53-4 methyl 4-morpholinobutanoate 
• 7357-67-7 4-(3-chloropropyl)morpholine 

Relevant academic research and scientific papers

ELECTROCHEMICAL FLUORINATION OF N-CHLOROALKYL-SUBSTITUTED CYCLIC AMINES

The electrochemical fluorination of such N-chloroalkyl substituted cyclic amines as N-chloromethylpyrrolidine (1), N-(3-chloropropyl)pyrrolidine (2), N-chloromethylpiperidine (3), N-(2-chloroethyl)piperidine (4), N-(3-chloropropyl)piperidine (5), N-chloromethylmorpholine (6), N-(3-chloropropyl)morpholine (7), N-(2-chloroallyl)morpholine (8) has been conducted.Except in the cases of the N-chloromethyl-substituted ones (1,3 and 6), the corresponding chlorine-retaining-perfluoroamines were obteined in a yield of 5 - 20 percent together with perfluorinated ones (Yield = 20 - 60 percent).Neither chlorine-retaining amines nor perfluorinated amines, both of which having the original skeleton, was produced from fluorinations of 1, 3 and 6 in an appreciable yield.The spectroscopic data and physical properties of newly synthesized perfluoro-N-chloroalkyl-substituted cyclic amines are presented.

Electrochemical fluorination of several methyl and/or ethyl esters of morpholino-substituted carboxylic acids

Seven methyl and/or ethyl esters of carboxylic acids (-CH2CH2C(O)OEt, -CH2CH2CH2C(O)OMe, -CH2CH2CH2C(O)OEt, -CH(C2H5)C(O)OMe, -CH(n-C3H7)C(O)OMe, -CH2CH2CH2CH2C(O)OEt and -CH2CH2CH2CH2CH2C(O) OEt) having a morpholino group were subjected to electrochemical fluorination (ECF). On ECF, the corresponding perfluoroacid fluorides bearing a perfluoromorpholino group were obtained in fair to good yields. Yields of the targeted perfluoromorpholino-containing perfluoroacid fluorides were influenced by the α-bond cleavage of the carboxylic acid and also by the kind of alkyl group of the carboxylic acid (the latter offering the possibility of cyclization side reactions). Perfluorooxolanes were formed as a major cyclization by-product from the ECF of morpholino-substituted carboxylic acids when the chain length of the alkyl group of the carboxylic acids had a carbon number of three or more and the structure of the alkyl group was branched in such a way as to allow cyclization. Perfluorodioxolanes were obtained in only small yields as the specific cyclization products when the ethyl esters of carboxylic acids were subjected to ECF. Spectroscopic data, as well as physicochemical properties, are described for the new perfluoroheterocyclic compounds with a perfluoromorpholino group that were produced.

The electrochemical fluorination of N-containing carboxylic acids (Part 4). Fluorination of methyl 3-dialkylamino-isobutyrates and methyl 3-dialkylamino-n-butyrates

Several methyl esters of 3-dialkylamino-substituted n- and isobutyric acids have been subjected to electrochemical fluorination to give the corresponding perfluoroacid fluorides.Dimethyl, diethyl, pyrrolidino, morpholino, piperidino and N-methylpiperazino groups were investigated as dialkylamino substituents.The structure/yield relationship was evaluated both in terms of the structure of the acid and the kind of amino group, respectively.Better yields of perfluoroacid fluorides were obtained from methyl esters having isobutyric acid skeletons than those having n-butyric acid groups, and from the acids containing cyclic amino groups than those containing acyclic ones.