1704073-79-9

Basic information

• Product Name: (3-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylsulfonyl)phenyl)boronic acid
• Synonyms: (3-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylsulfonyl)phenyl)boronic acid
• CAS NO: 1704073-79-9
• Molecular Formula: C13H18BNO6S
• Molecular Weight: 327.16112
• Mol File: 1704073-79-9.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 570.9±60.0 °C(Predicted)
• Appearance: /
• Density: 1.46±0.1 g/cm3(Predicted)
• PKA: 7.61±0.10(Predicted)
• CAS DataBase Reference: (3-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylsulfonyl)phenyl)boronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (3-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylsulfonyl)phenyl)boronic acid(1704073-79-9)
• EPA Substance Registry System: (3-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylsulfonyl)phenyl)boronic acid(1704073-79-9)

Safety Data

• Hazardous Substances Data: 1704073-79-9(Hazardous Substances Data)

Usage

Description

(3-(1,4-Dioxa-8-azaspiro[4.5]decan-8-ylsulfonyl)phenyl)boronic acid, also known as DB824, is a boronic acid derivative with potential antineoplastic activity. It is an investigational drug in the treatment of multiple myeloma and other B-cell malignancies.
Used in Pharmaceutical Industry:
(3-(1,4-Dioxa-8-azaspiro[4.5]decan-8-ylsulfonyl)phenyl)boronic acid is used as an antineoplastic agent for the treatment of multiple myeloma and other B-cell malignancies. It inhibits the activity of the proteasome, a cell protein complex that plays a key role in the regulation of cell cycle and apoptosis, ultimately leading to the death of cancer cells.
Used in Cancer Therapy:
(3-(1,4-Dioxa-8-azaspiro[4.5]decan-8-ylsulfonyl)phenyl)boronic acid is used as a potential cancer therapy agent. It has shown promising results in preclinical studies and is being evaluated in clinical trials for its potential in cancer therapy. As a boronic acid derivative, it has the potential to be a valuable addition to the arsenal of drugs available for the treatment of certain types of cancer.