170451-36-2

Upstream product

• 4551-15-9 phenylthiotrimethylsilane 
• 170555-82-5 acetyl 2,4-di-O-acetyl-D-xylopyranoside 
• 87-72-9 D-Xylose 

Downstream Products

• 170451-43-1 phenyl 2,4-di-O-acetyl-3-O-[4-O-(tert-butyldimethylsilyl)-2,3-di-O-methyl-α-L-fucopyranosyl]-1-thio-β-D-xylopyranoside 
• 861120-63-0 Acetic acid (2S,3R,4S,5R)-5-acetoxy-4-((2S,3S,4R,5R,6S)-5-benzyloxy-3,4-dimethoxy-6-methyl-tetrahydro-pyran-2-yloxy)-2-phenylsulfanyl-tetrahydro-pyran-3-yl ester 

Relevant academic research and scientific papers

Stereocontrolled elaboration of natural (-)-polycavernoside A, a powerfully toxic metabolite of the red alga Polycavernosa tsudai

A stereoselective total synthesis of natural levorotatory polycavernoside A (1) has been achieved. Initial investigations produced the properly activated disaccharide unit 18b via the conjoining of building blocks originating from L-fucose and D-xylose. T

STUDIES DIRECTED TOWARD THE TOTAL SYNTHESIS OF POLYCAVERNOSIDE A. ENANTIOSELECTIVE SYNTHESIS OF THE DISACCHARIDE COMPONENT

Adaptation of the Mukaiyama-Nicolaou protocol to the coupling of a monounprotected thioglycoside to a glycosyl fluoride is capable of delivering the unusual disaccharide present in the title toxin.