170455-05-7Relevant academic research and scientific papers
Synthesis of N(α), N(β)-alkylated diaminopropionic acid analogs
Solomon,Lynch,Rich
, p. 4955 - 4958 (1995)
A general route for the preparation of N(α)-alkylated and N(β)- alkylated derivatives of diaminopropionic acids is described. Nucleophilic ring opening of N-tosyl aziridine-2-t-butyl carboxylate with primary amines leads to the corresponding N(β)-alkyl derivative. Reaction of the N(α)- tosyl diaminopropionic derivative with Cs2CO3 and alkyl iodide selectively produces the N(α)-alkylated compound.
