17046-92-3Relevant academic research and scientific papers
Development of C-N coupling using mechanochemistry: Catalytic coupling of arylsulfonamides and carbodiimides
Tan, Davin,Mottillo, Cristina,Strukil, Vjekoslav,Friscic, Tomislav,Katsenis, Athanassios D.
, p. 9321 - 9324,4 (2014)
Reported herein is the mechanochemical synthesis of sulfonyl guanidines, a family of molecules which are relevant as pharmaceuticals and herbicides, by direct coupling of sulfonamides and aromatic or aliphatic carbodiimides. Attempts to conduct the coupling in solution have either failed or given very low conversions, thus demonstrating mechanochemistry as the necessary component for the discovery of this synthetic strategy. Milling around: Mechanochemistry is used to develop a method for the direct coupling of carbodiimides and arylsulfonamides using a copper catalyst. Attempts to reproduce this C-N coupling reaction under conventional solution-based conditions either failed or gave very poor conversions.
Method for preparing sulfonyl guanidine compound
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Paragraph 0061; 0062; 0063; 0089; 0090; 0091, (2019/07/29)
The invention relates to a method for preparing a sulfonyl guanidine compound, and mainly provides a new method that the sulfonyl guanidine compound is constructed by the reaction of a sulfonyl azideand an amine in which 4,5-dimethylaryl bisisonitrile is
