170512-18-2Relevant academic research and scientific papers
Synthetic studies on aphidicolane and stemodane diterpenes. V. A facile formal total synthesis of (±)-aphidicolin via a Lewis acid-mediated stereoselective spiroannelation
Tanaka,Okuda,Murakami,Yoshino,Mikamiyama,Kanda,Kim -,Iwata
, p. 1407 - 1411 (2007/10/02)
Formal total synthesis of (±)-aphidicolin (1) was achieved via a Lewis acid-mediated stereoselective spiroannelation reaction as a key step. The bisbenzyl acetal (2) was synthesized from the readily available dimethyl acetal (4). Treatment of 2 with trime
