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Celecoxib 2-Methyl Analog, also known as 4-Desmethyl-2-methyl Celecoxib, is a chemical analog of Celecoxib (C251000). It is a cyclooxygenase 2 (COX-2) inhibitor, which is a type of nonsteroidal anti-inflammatory drug (NSAID) that selectively targets the COX-2 enzyme involved in inflammation and pain.

170569-99-0

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170569-99-0 Usage

Uses

Used in Pharmaceutical Industry:
Celecoxib 2-Methyl Analog is used as a COX-2 inhibitor for the treatment of inflammation and pain. It selectively targets the COX-2 enzyme, which is responsible for the production of prostaglandins that cause inflammation and pain. This selective inhibition helps to reduce inflammation and pain while minimizing the side effects associated with non-selective NSAIDs.
Used in Research Applications:
Celecoxib 2-Methyl Analog is also used as a research tool for studying the role of COX-2 in various biological processes and diseases. It can be used to investigate the mechanisms of action of COX-2 inhibitors and their potential therapeutic applications in various conditions, such as cancer, neurodegenerative diseases, and cardiovascular diseases.
Used in Drug Development:
Celecoxib 2-Methyl Analog can be used in the development of new drugs with improved selectivity, potency, and safety profiles. By understanding the structure-activity relationship of Celecoxib 2-Methyl Analog and its analogs, researchers can design and synthesize novel COX-2 inhibitors with better pharmacological properties and therapeutic potential.

Check Digit Verification of cas no

The CAS Registry Mumber 170569-99-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,0,5,6 and 9 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 170569-99:
(8*1)+(7*7)+(6*0)+(5*5)+(4*6)+(3*9)+(2*9)+(1*9)=160
160 % 10 = 0
So 170569-99-0 is a valid CAS Registry Number.

170569-99-0Upstream product

170569-99-0Downstream Products

170569-99-0Relevant academic research and scientific papers

1,5-diarylpyrazole derivative, and synthetic method and application thereof

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Paragraph 0039; 0041; 0044; 0047-0048, (2021/07/01)

The invention relates to a 1,5-diaryl pyrazole derivative and antibacterial application thereof. On the basis of a celecoxib structure, structural modification is conducted on 1,5-diaryl to obtain the 1,5-diaryl pyrazole derivative; and after structural c

Substituted pyrazolyl benzenesulfonamides for the treatment of inflammation

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, (2008/06/13)

A class of pyrazolyl benzenesulfonamide compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula II: STR1 or a pharmaceutically-acceptable salt thereof.

Substituted pyrazolyl benzenesulfonamides for use in veterinary therapies

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, (2008/06/13)

A method of using pyrazolyl benzenesulfonamide compounds in treating inflammation and inflammation-related disorders in companion animals is disclosed.

Substituted pyrazolyl benzenesulfonamide for the treatment of inflammation

-

, (2008/06/13)

A class of pyrazolyl benzenesulfonamide compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula I: STR1

SUBSTITUTED PYRAZOLYL BENZENESULFONAMIDES

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, (2008/06/13)

A class of pyrazolyl benzenesulfonamide compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula I: or a pharmaceutically-acceptable salt thereof

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