170654-43-0Relevant academic research and scientific papers
Facile synthesis of α-fluoroalkyl sulfides under the oxidative desulfurization-fluorination conditions
Furuta,Kuroboshi,Hiyama
, p. 2687 - 2694 (2007/10/03)
Upon treatment with n-Bu4NH2F3 and 1,3-dibromo-5,5- dimethylhydantoin, various organic sulfides underwent a Pummerer-type rearrangement, followed by fluorination, to give α-fluoro sulfides. The fluoro-Pummerer rearrangement, when applied to RCH(SMe)CF2SMe, gave trifluoro sulfides RCF(SMe)CF2SMe. When an HF-pyridine reagent was used as the fluorinating agent, an oxidative desulfurization-fluorination reaction occurred depending on the structure of the substrates.
Oxidative Desulfurization-Fluorination of 1-Substituted 2,2,2-Tris(methylthio)ethanol Induces Difluorination under Oxidation or Rearrangement
Kuroboshi, Manabu,Furuta, Satoru,Hiyama, Tamejiro
, p. 6121 - 6122 (2007/10/02)
Oxidative desulfurization-fluorination of RCH(OH)C(SMe)3 using n-Bu4NH2F3 and 1,3-dibromo-5,5-dimethylhydantoin gave RC(O)CF2SMe, whereas treatment of the same substrates with Et2NSF3 afforded RCH(SMe)CF2SMe.
