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N-[5-[2-[Bis[4-(difluoroMethoxy)phenyl]MethylaMino]-1(R)-hydroxyethyl]-2-hydroxyphenyl]MethanesulfonaMide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

170686-12-1

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170686-12-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 170686-12-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,0,6,8 and 6 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 170686-12:
(8*1)+(7*7)+(6*0)+(5*6)+(4*8)+(3*6)+(2*1)+(1*2)=141
141 % 10 = 1
So 170686-12-1 is a valid CAS Registry Number.

170686-12-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name N-[5-[(1R)-2-[bis[4-(difluoromethoxy)phenyl]methylamino]-1-hydroxyethyl]-2-hydroxyphenyl]methanesulfonamide

1.2 Other means of identification

Product number -
Other names UNII-93ZDV2P17I

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:170686-12-1 SDS

170686-12-1Downstream Products

170686-12-1Relevant academic research and scientific papers

Beta 3 agonists. Part 1: Evolution from inception to BMS-194449

Washburn,Sher,Poss,Girotra,McCann,Gavai,Mikkilineni,Mathur,Cheng,Dejneka,Sun,Wang,Harper,Russell,Slusarchyk,Skwish,Allen,Hillyer,Frohlich,Abboa-Offei,Cap,Waldron,George,Tesfamariam,Ciosek Jr.,Ryono,Young,Dickinson,Seymour,Arbeeny,Gregg

, p. 3035 - 3039 (2007/10/03)

Screening of the BMS collection identified 4-hydroxy-3-methylsulfonanilidoethanolamines as full beta 3 agonists. Substitution of the ethanolamine nitrogen with a benzyl group bearing a para hydrogen bond acceptor promoted β3 selectivity. SAR elucidation established that highly selective β3 agonists were generated upon substitution of Cα with either benzyl to form (R)-1,2-diarylethylamines or with aryl to generate 1,1-diarylmethylamines. This latter subset yielded a clinical candidate, BMS-194449 (35).

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