170706-60-2

Upstream product

• 170706-56-6 (E)-4-[(2S,3R,5S,6R)-5-Benzyloxy-6-benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxy)-2-methyl-tetrahydro-pyran-2-yl]-but-2-enoic acid methyl ester 
• 170706-58-8 {(2R,3R)-3-[(2S,3R,5S,6R)-5-Benzyloxy-6-benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxy)-2-methyl-tetrahydro-pyran-2-ylmethyl]-oxiranyl}-methanol 
• 170706-57-7 (E)-4-[(2S,3R,5S,6R)-5-Benzyloxy-6-benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxy)-2-methyl-tetrahydro-pyran-2-yl]-but-2-en-1-ol 
• 170706-55-5 [(2S,3R,5S,6R)-5-Benzyloxy-6-benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxy)-2-methyl-tetrahydro-pyran-2-yl]-acetaldehyde 
• 170706-53-3 ((2S,3R,5S,6R)-5-Benzyloxy-6-benzyloxymethyl-2-methyl-2-vinyl-tetrahydro-pyran-3-yloxy)-tert-butyl-dimethyl-silane 
• 170706-54-4 2-[(2S,3R,5S,6R)-5-Benzyloxy-6-benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxy)-2-methyl-tetrahydro-pyran-2-yl]-ethanol 
• 170706-52-2 (2R,3S,5R,6S)-5-(tert-Butyl-dimethyl-silanyloxy)-2-hydroxymethyl-6-methyl-6-vinyl-tetrahydro-pyran-3-ol 
• 131310-62-8 tert-Butyl-dimethyl-((2R,4aR,6S,7R,8aS)-6-methyl-2-phenyl-6-vinyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yloxy)-silane 

Downstream Products

• 170706-61-3 (E)-3-[(2R,3R)-3-((2S,3R,5S,6R)-5-Benzyloxy-6-benzyloxymethyl-3-hydroxy-2-methyl-tetrahydro-pyran-2-ylmethyl)-oxiranyl]-2-methyl-acrylic acid ethyl ester 
• 170706-62-4 (E)-3-((2S,3R,4aS,6R,7S,8aR)-7-Benzyloxy-6-benzyloxymethyl-3-hydroxy-4a-methyl-octahydro-pyrano[3,2-b]pyran-2-yl)-2-methyl-acrylic acid ethyl ester 

Relevant academic research and scientific papers

Total synthesis of brevetoxin B. 1. First generation strategies and new approaches to oxepane systems

The first generation strategies toward the total synthesis of brevetoxin B (1) are presented and the syntheses of the key intermediates 3, 4, 5, 67, 83, and 94-98 required for the projected construction are described. The earliest and most convergent stra