170744-87-3Relevant academic research and scientific papers
Efficient and sustainable laccase-catalyzed iodination of: P -substituted phenols using KI as iodine source and aerial O2 as oxidant
Sdahl, Mark,Conrad, Jürgen,Braunberger, Christina,Beifuss, Uwe
, p. 19549 - 19559 (2019/07/05)
The laccase-catalyzed iodination of p-hydroxyarylcarbonyl- and p-hydroxyarylcarboxylic acid derivatives using KI as iodine source and aerial oxygen as the oxidant delivers the corresponding iodophenols in a highly efficient and sustainable manner with yields up to 93% on a preparative scale under mild reaction conditions.
Highly chemoselective hydrogenolysis of iodoarenes
Faucher, Nicolas,Ambroise, Yves,Cintrat, Jean-Christophe,Doris, Eric,Pillon, Florence,Rousseau, Bernard
, p. 932 - 934 (2007/10/03)
The catalytic hydrodehalogenation reaction using molecular hydrogen and Pd/C has been revisited. It is shown that the speed of removal of halogen increases with increasing electronegativity I Br Cl. Nevertheless, selective dehydrohalogenation in compounds containing other reducible functions can be achieved only with iodine and not with bromine or chlorine. Selective deiodination of iodobenzophenone could be accomplished without reducing the carbonyl group. Hydrogenolysis of azidoiodoaromatic compounds to the corresponding azido compounds is high yielding. This selectivity was exploited for the labeling of benzophenone- and azido-containing compounds by deuterium and tritium.
Carboxylic acid derivatives as IP antagonists
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, (2008/06/13)
This invention relates to compounds which are generally IP receptor antagonists and which are represented by Formula I: wherein: R1, R2, and R3 are each independently in each occurrence aryl or heteroaryl; R4 is
