17075-00-2

Basic information

• Product Name: 3-Butyn-1-ol, 2-methyl-4-phenyl-
• CAS NO: 17075-00-2
• Molecular Formula: C11H12O
• Molecular Weight: 160.216
• Mol File: 17075-00-2.mol

Chemical Properties

• CAS DataBase Reference: 3-Butyn-1-ol, 2-methyl-4-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Butyn-1-ol, 2-methyl-4-phenyl-(17075-00-2)
• EPA Substance Registry System: 3-Butyn-1-ol, 2-methyl-4-phenyl-(17075-00-2)

Safety Data

• Hazardous Substances Data: 17075-00-2(Hazardous Substances Data)

Upstream product

• 107-18-6 allyl alcohol 
• 932-87-6 1-Bromo-2-phenylacetylene 
• 7065-27-2 2-methyl-2-(2-phenylethynyl)oxirane 
• 536-74-3 phenylacetylene 
• 50-00-0 formaldehyd 
• 27975-80-0 (+/-)-3-bromo-1-phenyl-1-butyne 

Downstream Products

• 105905-49-5 4-chloro-3-methyl-1-phenylbutan-1-one 
• 38300-00-4 (2R*,4S*)-4-methyl-2-phenyltetrahydrofuran 
• 38300-00-4 (2S*,4S*)-4-methyl-2-phenyltetrahydrofuran 
• 17066-29-4 tert-Butyl-4-phenyl-3-butyne-2-percaboxylat 
• 17066-24-9 2-Methyl-4-phenyl-3-butynoylchlorid 
• 17066-19-2 2-methyl-4-phenyl-3-butynoic acid 

Relevant articles and documents

Csp-Csp3 Bond Formation via Iron(III)-Promoted Hydroalkynylation of Unactivated Alkenes

An iron(III)-promoted hydroalkynylation of unactivated alkenes toward Csp-Csp3 bond formation has been developed. Various alkenes, including mono-, di-, and trisubstituted alkenes, could all smoothly convert to structural diversified alkynes in this chemoselective protocol. Additionally, the scalability was unraveled and the further divergent transformations of products were conducted to demonstrate the synthetic utility.

Palladium(II)-Catalyzed Regioselective syn-Hydroarylation of Disubstituted Alkynes Using a Removable Directing Group

A palladium(II)-catalyzed regioselective syn-hydroarylation reaction of homopropargyl amines has been developed, wherein selectivity is controlled by a cleavable bidentate directing group. Under the optimized reaction conditions, both dialkyl and alkylaryl alkyne substrates were found to undergo hydroarylation with high selectivity. The products of this reaction contain a 4,4-disubstituted homoallylic amine motif that is commonly seen in drug molecules and other bioactive compounds.

Relative asymmetric induction in the intramolecular reaction between alkynes and cyclopropylcarbene-chromium complexes: Stereocontrolled synthesis of five-membered rings fused to oxygen heterocycles

Synthesis of cyclopentenone derivatives fused to oxygen heterocycles by means of the intramolecular coupling of alkynes and cyclopropylcarbene- chromium complexes has been examined for a variety of cases in which the tethering chain features a stereogenic

Regioselective ring opening of α-substituted α-alkynyl oxiranes to 2-substituted 3-butyn-1-ols

Treatment of α-substituted α-acetylenic epoxides with DIBAH in THF provides 2-substituted 3-butyn-1-ols in high yield avoiding propargyl/allene isomerization.

Palladium-catalysed Preparation of 1,2-Dienes by Selective Hydrogenolysis of Alk-2-ynyl Cabonates with Ammonium Formate

1,2-Dienes were prepared by the selective hydrogenolysis of alk-2-ynyl carbonates with HCO2NH4 catalysed by Pd2(dba)3*CHCl3-P(n-Bu)3 (dba = dibenzylideneacetone).