17076-90-3

Basic information

• Product Name: 1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)vinyl]pyrimidine citrate
• Synonyms: 1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)vinyl]pyrimidine citrate;1,4,5,6-Tetrahydro-1-methyl-2-[2-(2-thienyl)ethenyl]pyrimidine/2-hydroxy-1,2,3-propanetricarboxylic acid,(1:x);Einecs 241-134-1
• CAS NO: 17076-90-3
• Molecular Formula: C₆H₈O₇*C₁₁H₁₄N₂S
• Molecular Weight: 398.43078
• EINECS: 241-134-1
• Mol File: 17076-90-3.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 324.4°Cat760mmHg
• Flash Point: 150°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 0.000246mmHg at 25°C
• CAS DataBase Reference: 1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)vinyl]pyrimidine citrate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)vinyl]pyrimidine citrate(17076-90-3)
• EPA Substance Registry System: 1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)vinyl]pyrimidine citrate(17076-90-3)

Safety Data

• Hazardous Substances Data: 17076-90-3(Hazardous Substances Data)

Usage

Chemical structure

A pyrimidine derivative with a 1-methyl group and a 2-(2-thienyl)vinyl group.

Pharmaceutical use

As a hypolipidemic agent to lower lipid levels in the blood.

Mechanism of action

Inhibits the enzyme HMG-CoA reductase, which is involved in cholesterol synthesis.

Health benefits

Reduces the risk of cardiovascular diseases and improves lipid profiles.

Efficacy

Effective in reducing total cholesterol, LDL cholesterol, and triglyceride levels in clinical studies.

Limitations

Limited use due to concerns about potential liver damage and hepatotoxicity.

InChI:InChI=1/C11H14N2S.C6H8O7/c1-13-8-3-7-12-11(13)6-5-10-4-2-9-14-10;7-3(8)1-6(13,5(11)12)2-4(9)10/h2,4-6,9H,3,7-8H2,1H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/b6-5+;