170838-83-2

Basic information

• Product Name: 1-[(TERT-BUTYL)OXYCARBONYL]-3-BENZYLPIPERIDINE-3-CARBOXYLIC ACID
• Synonyms: 1-[(TERT-BUTYL)OXYCARBONYL]-3-BENZYLPIPERIDINE-3-CARBOXYLIC ACID;3-BENZYL-PIPERIDINE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER;1-BOC-3-BENZYL-PIPERIDINE-3-CARBOXYLIC ACID;1,3-Piperidinedicarboxylic acid, 3-(phenylmethyl)-, 1-(1,1-dimethylethyl) ester;3-Benzyl-1-(tert-butoxycarbonyl)piperidine-3-carboxylic acid;1-Boc-3-benzyl-3-piperidinecarboxylic acid
• CAS NO: 170838-83-2
• Molecular Formula: C18H25NO4
• Molecular Weight: 319.4
• Product Categories: pharmacetical
• Mol File: 170838-83-2.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 456.9 °C at 760 mmHg
• Flash Point: 230.1 °C
• Appearance: /
• Density: 1.167g/cm³
• Vapor Pressure: 3.86E-09mmHg at 25°C
• Refractive Index: 1.545
• PKA: 4.40±0.20(Predicted)
• CAS DataBase Reference: 1-[(TERT-BUTYL)OXYCARBONYL]-3-BENZYLPIPERIDINE-3-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(TERT-BUTYL)OXYCARBONYL]-3-BENZYLPIPERIDINE-3-CARBOXYLIC ACID(170838-83-2)
• EPA Substance Registry System: 1-[(TERT-BUTYL)OXYCARBONYL]-3-BENZYLPIPERIDINE-3-CARBOXYLIC ACID(170838-83-2)

Safety Data

• Hazardous Substances Data: 170838-83-2(Hazardous Substances Data)

Usage

Description

1-[(TERT-BUTYL)OXYCARBONYL]-3-BENZYLPIPERIDINE-3-CARBOXYLIC ACID is a chemical compound with the molecular formula C24H29NO5. It is a piperidine derivative featuring a carboxylic acid functional group and a tert-butyl group attached to the nitrogen atom. The benzyl substituent is an aromatic ring connected to the piperidine nitrogen, making it a versatile molecule in organic synthesis and pharmaceutical chemistry.

Uses

Used in Organic Synthesis:
1-[(TERT-BUTYL)OXYCARBONYL]-3-BENZYLPIPERIDINE-3-CARBOXYLIC ACID is used as a protecting group for amines in organic synthesis. Its tert-butyloxycarbonyl group shields the amine functionality, preventing unwanted reactions and facilitating selective transformations of other functional groups in the molecule.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 1-[(TERT-BUTYL)OXYCARBONYL]-3-BENZYLPIPERIDINE-3-CARBOXYLIC ACID serves as a precursor for the synthesis of various bioactive compounds and pharmaceuticals. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Prodrug Development:
1-[(TERT-BUTYL)OXYCARBONYL]-3-BENZYLPIPERIDINE-3-CARBOXYLIC ACID is utilized in the design and synthesis of prodrugs. Prodrugs are inactive compounds that can be metabolized in the body to release the active drug, improving drug delivery, bioavailability, and reducing side effects.
Used in Medicinal Chemistry and Drug Discovery:
In the field of medicinal chemistry, 1-[(TERT-BUTYL)OXYCARBONYL]-3-BENZYLPIPERIDINE-3-CARBOXYLIC ACID has potential applications in drug discovery. Its structural features can be modified to explore new chemical space and identify novel lead compounds with therapeutic potential.

InChI:InChI=1/C18H25NO4/c1-17(2,3)23-16(22)19-11-7-10-18(13-19,15(20)21)12-14-8-5-4-6-9-14/h4-6,8-9H,7,10-13H2,1-3H3,(H,20,21)