170856-41-4 Usage
Uses
PNU 96415E is an antipsychotic agent; SR-2A inhibitor.
Biological Activity
Antipsychotic agent. Displays high affinity for dopamine D 4 and serotonergic 5-HT 2A receptors and relatively weak affinity at D 2 receptors (K i values are 3.0, 5.8, 134, 181, 199, 240, 411 and > 678 nM for D 4 , 5-HT 2A , 5-HT 1A , α 1 , D 2 , D 3 , D 1 , α 2 ? and muscarinic receptors respectively). Inhibits exploratory locomotor activity and antagonizes d-amphetamine-induced locomotor stimulation in rats.
Check Digit Verification of cas no
The CAS Registry Mumber 170856-41-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,0,8,5 and 6 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 170856-41:
(8*1)+(7*7)+(6*0)+(5*8)+(4*5)+(3*6)+(2*4)+(1*1)=144
144 % 10 = 4
So 170856-41-4 is a valid CAS Registry Number.
170856-41-4Relevant articles and documents
Heterocyclic compounds for the treatment of CNS and cardiovascular disorders
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, (2008/06/13)
Novel aromatic bicyclic amines of formula (I) STR1 are useful in treating central nervous system disorders and cardiac arrhythmias and cardiac fibrillation.