170902-34-8

Basic information

• Product Name: (5S)-5-methyl-3-[(2R,8R,11R)-2,8,11-trihydroxy-11-{(5R)-5-[(1S)-1-hydroxypentadecyl]tetrahydrofuran-2-yl}undecyl]furan-2(5H)-one
• CAS NO: 170902-34-8
• Molecular Formula: C₃₅H₆₄O₇
• Molecular Weight: 596.8785
• Mol File: 170902-34-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 751°C at 760 mmHg
• Flash Point: 225.1°C
• Density: 1.05g/cm³
• Vapor Pressure: 4.97E-26mmHg at 25°C
• Refractive Index: 1.506
• CAS DataBase Reference: (5S)-5-methyl-3-[(2R,8R,11R)-2,8,11-trihydroxy-11-{(5R)-5-[(1S)-1-hydroxypentadecyl]tetrahydrofuran-2-yl}undecyl]furan-2(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (5S)-5-methyl-3-[(2R,8R,11R)-2,8,11-trihydroxy-11-{(5R)-5-[(1S)-1-hydroxypentadecyl]tetrahydrofuran-2-yl}undecyl]furan-2(5H)-one(170902-34-8)
• EPA Substance Registry System: (5S)-5-methyl-3-[(2R,8R,11R)-2,8,11-trihydroxy-11-{(5R)-5-[(1S)-1-hydroxypentadecyl]tetrahydrofuran-2-yl}undecyl]furan-2(5H)-one(170902-34-8)

Safety Data

• Hazardous Substances Data: 170902-34-8(Hazardous Substances Data)

Upstream product

• 471261-23-1 (2S)-toluene-4-sulfonic acid 5-(tert-butyl-diphenyl-silanyloxy)-2-hydroxy-pentyl ester 
• 58879-34-8 (S)-5-tosyloxypentan-4-olide 
• 865091-37-8 (R)-5-((S)-1-Methoxymethoxy-pentadecyl)-tetrahydro-furan-2-ol 
• 865091-17-4 (5R,1'S)-5-(1'-methoxymethoxy-pentadecyl)-dihydro-furan-2-one 
• 865091-50-5 (4R)-tert-butyl-(4-methoxymethoxy-oct-7-enyloxy)-diphenyl-silane 
• 865091-34-5 (5R)-5-pentadecanoyl-dihydro-furan-2-one 
• 32780-06-6 (5S)-5-(hydroxymethyl)-2-oxo-tetrahydrofuran 
• 53558-93-3 (R)-tetrahydro-5-oxo-2-furancarboxylic acid 
• 21461-84-7 (2S)-tetrahydro-5-oxofuran-2-carboxylic acid 
• 865091-26-5 (4S,7R,2'R,5'R,1''S)-7-methoxymethoxy-7-[5'-(1''-methoxymethoxy-pentadecyl)-tetrahydro-furan-2'-yl]-hept-1-en-4-ol 
• 865091-21-0 (4R,2'R,5'R,1''S)-N-methoxy-4-hydroxy-4-[5'-(1''-methoxymethoxy-pentadecyl)-tetrahydro-furan-2'-yl]-N-methyl-butyramide 
• 865091-23-2 (4R)-4-methoxymethoxy-oct-7-enoic acid 
• 865091-48-1 (R)-4-Methoxymethoxy-oct-7-en-1-ol 
• 865091-33-4 Trifluoro-acetic acid (1R,7R)-7-methoxymethoxy-1-{(R)-3-methoxymethoxy-3-[(2R,5R)-5-((S)-1-methoxymethoxy-pentadecyl)-tetrahydro-furan-2-yl]-propyl}-8-((S)-5-methyl-2-oxo-2,5-dihydro-furan-3-yl)-octyl ester 

Relevant articles and documents

Total synthesis and structural confirmation of (+)-longicin

(Chemical Equation Presented) A stereocontrolled total synthesis of (+)-longicin, a representative of the class of mono-THF-acetogenins, is described. The strategy involves the utilization of D- and L-glutamic acids as chirons that correspond to two five-carbon segments harboring stereogenic centers at C4 and at C17 of the C32 polyketide-derived natural product. The use of Grubbs' RCM reaction as a novel "chain elongation" strategy for the synthesis of acetogenin-type structures and a new protocol for butenolide incorporation are also described.