170917-89-2

Basic information

• Product Name: 7-Chloroindeno[1,2-e][1,3,4]oxadiazine-2,4a(3H,5H)-dicarboxylic acid 4a-methyl 2-benzyl ester
• Synonyms: 7-Chloroindeno[1,2-e][1,3,4]oxadiazine-2,4a(3H,5H)-dicarboxylic acid 4a-methyl 2-benzyl ester;Indeno[1,2-e][1,3,4]oxadiazine-2,4a(3H,5H)-dicarboxylic acid, 7-chloro-, 4a-Methyl 2-(phenylMethyl) ester;7-Chloro-5H-indeno[1,2-e][1,3,4]oxadiazine-2,4a-dicarboxylic acid 2-benzyl ester 4a-Methyl ester;2-benzyl 4a-methyl 7-chloroindeno[1,2-e][1,3,4]oxadiazine-2,4a(3H,5H)-dicarboxylate
• CAS NO: 170917-89-2
• Molecular Formula: C₂₀H₁₇ClN₂O₅
• Molecular Weight: 400.81238
• Mol File: 170917-89-2.mol
• Article Data: 4

Chemical Properties

• Melting Point: 122-125℃
• Boiling Point: 531.734°C at 760 mmHg
• Flash Point: 275.383°C
• Appearance: /
• Density: 1.41
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.641
• CAS DataBase Reference: 7-Chloroindeno[1,2-e][1,3,4]oxadiazine-2,4a(3H,5H)-dicarboxylic acid 4a-methyl 2-benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Chloroindeno[1,2-e][1,3,4]oxadiazine-2,4a(3H,5H)-dicarboxylic acid 4a-methyl 2-benzyl ester(170917-89-2)
• EPA Substance Registry System: 7-Chloroindeno[1,2-e][1,3,4]oxadiazine-2,4a(3H,5H)-dicarboxylic acid 4a-methyl 2-benzyl ester(170917-89-2)

Safety Data

• Hazardous Substances Data: 170917-89-2(Hazardous Substances Data)

Usage

General Description

7-Chloroindeno[1,2-e][1,3,4]oxadiazine-2,4a(3H,5H)-dicarboxylic acid 4a-methyl 2-benzyl ester is a chemical compound with a complicated structure, containing chloro and carboxylic acid functional groups. It is commonly used as a starting compound in the synthesis of various pharmaceuticals and agrochemicals, as well as in research and development of new chemical compounds. This chemical has the potential to exhibit biological activity due to its structure and functional groups, and can be modified and utilized in various fields of science and industry. It is important to handle and use this compound with caution, as it may possess hazardous properties and require proper safety protocols and regulations to be followed.

InChI:InChI=1/C20H17ClN2O5/c1-26-18(24)20-10-14-9-15(21)7-8-16(14)17(20)22-23(12-28-20)19(25)27-11-13-5-3-2-4-6-13/h2-9H,10-12H2,1H3

Upstream product

• 173903-23-6 C₁₂H₁₁ClN₂O₃ 
• 501-53-1 benzyl chloroformate 
• 462-95-3 formaldehyde diethyl acetal 
• 5331-43-1 N-benzyloxycarbonyl-hydrazine 
• 144172-24-7 (R,S)‐5‐chloro‐1‐oxo‐2,3‐dihydro‐2‐hydroxy‐1H‐indene‐2‐carboxylic acid methyl ester 
• 50-00-0 formaldehyd 
• 173903-19-0 C₁₉H₁₇ClN₂O₅ 

Relevant articles and documents

Preparation method of indoxacarb key intermediate

The invention belongs to the field of chemical synthesis, and relates to a novel method for preparing an indoxacarb key intermediate. The key intermediate is 7-indeno [1, 2, e] [1, 3, 4] oxadiazine-2,4a (3H, 5H)-dicarboxylic acid-4a-methyl ester-2-benzyl ester. The preparation method is mainly characterized in that a phase transfer catalyst is added in the condensation reaction process, reactantsare in full contact under the action of the phase transfer catalyst, so that the reaction quickly realizes a homogeneous system, the reaction is more thorough, the product yield is high, the reactiontime is shortened by about 3-4 hours compared with the existing process, and the reaction rate is greatly improved. More importantly, the condensation system is a homogeneous system, is easy to dropwise add in the cyclization reaction process, does not block a bottom valve or a pipeline, is convenient to operate, saves manpower and material resources, and is beneficial to industrial production.

Preparation method of indoxacarb intermediate

The invention relates to a preparation method of indoxacarb intermediate. The preparation method is characterized by comprising the following steps: dissolving intermediate 5-chloro-2-methoxycarbonyl-2-hydroxy-1-indanone into xylene, adding benzyl carbazate and phosphorus pentoxide, separating out phosphoric acid, adding diethoxymethane into reaction liquid, enabling the solvent xylene to flow back on a tower, dropping the obtained reaction liquid into xylene at a constant speed, gathering ethyl alcohol, performing negative pressure desolventizing on obtained reaction liquid, adding a crystallizing agent into the rest liquid, performing cooling crystallization, filtering, and drying, so as to obtain 7-chloroindeno [1,2-e][1,3,4] oxadiazine-2,4a (3H,5H)-dicarboxylicacid-4a-methyl-2-benzylester. The method is convenient to operate, increases the reaction temperature, accelerates the reaction speed, and obviously improves the content and the yield of the intermediate.