170953-78-3 Usage
Uses
Used in Organic Synthesis:
3-Ethoxy-5-chloromethylisothiazole is used as a synthetic intermediate for the development of various organic compounds. Its unique structure allows it to be a versatile building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals. The presence of the ethoxy and chloromethyl groups provides opportunities for further chemical reactions, enabling the creation of a wide range of derivatives with diverse properties and applications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-Ethoxy-5-chloromethylisothiazole is utilized as a key component in the synthesis of drug candidates. Its chemical properties make it suitable for the development of new molecules with potential therapeutic effects. Researchers can exploit its reactivity to design and synthesize novel drug molecules that target specific biological pathways or receptors, contributing to the discovery of innovative treatments for various diseases.
Used in Agrochemical Industry:
3-Ethoxy-5-chloromethylisothiazole also finds application in the agrochemical industry, where it serves as a precursor for the synthesis of new pesticides or herbicides. Its unique structure can be modified to create compounds with enhanced biological activity and selectivity, leading to the development of more effective and environmentally friendly agrochemical products.
Check Digit Verification of cas no
The CAS Registry Mumber 170953-78-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,0,9,5 and 3 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 170953-78:
(8*1)+(7*7)+(6*0)+(5*9)+(4*5)+(3*3)+(2*7)+(1*8)=153
153 % 10 = 3
So 170953-78-3 is a valid CAS Registry Number.
170953-78-3Relevant academic research and scientific papers
Frolund,Ebert,Lawrence,Hurt,Krogsgaard-Larsen
, p. 877 - 889 (1995)
The synthesis of tritium labelled thiomuscimol (5-amino[3H]2methyl-3-isothiazolol) (7c), a specific and high-affinity agonist photoaffinity label for GABA(A) receptors, is described. The synthesis of 7c is based on a procedure for the preparation of 5-amino[2H]2methyl-3-isothiazolol (7b). Methyl 3-ethoxyisothiazole-5-carboxylate (3), synthesized from 3-hydroxyisothiazole-5-carboxamide (1) via the corresponding methyl ester (2), was reduced with sodium borotritide to give 3-ethoxy-5-hydroxy[3H]2methyl-3-isothiazole (4c). 3-Ethoxy-5-phthalimido[3H]2-methylisothiazole (6c), synthesized from the 5-chloro[3H]2methyl analogue (5c) of (4c), was deprotected by treatment with concentrated hydrochloric acid to give 7c with a specific radioactivity of 29 Ci/mmol. In pilot binding assays, 7c was shown to bind to membranes from rat forebrain in a saturable manner and with K(D) and B(max) values of 28 ± 6 nM and 50 ± 4 fmol/mg original tissue, respectively.
