170981-23-4

Upstream product

• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 159555-14-3 2,2,2-Trifluoro-N-(6-{2-[1-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl]-acetylamino}-hexyl)-acetamide 
• 124-09-4 1,6-Hexanediamine 
• 170981-20-1 1-(3',5'-di-O-acetyl-2'-bromo-2'-deoxy-β-D-ribofuranosyl)-5-(methoxycarbonylmethyl)-uracil 
• 159555-11-0 2,2'-anhydro-1-(β-D-arabinofuranosyl)-5-(methoxycarbonylmethyl)-uracil 
• 617-52-7 Dimethyl itakonate 
• 26805-54-9 dimethyl (Z)-2-(bromomethyl)fumarate 
• 159555-13-2 3',5'-di-O-acetyl-5-(methoxycarbonylmethyl)-2'-deoxyuridine 
• 170981-24-5 5-[N-(6-aminohexyl)carbamoylmethyl]-2'-deoxyuridine 

Relevant academic research and scientific papers

Novel C5-substituted 2'-deoxyuridine derivatives bearing amino-linker arms: Synthesis, incorporation into oligodeoxyribonucleotides, and their hybridization properties

2'-Deoxyuridine derivatives bearing several kinds of amino-linker arms at C5 position were synthesized from 5-(methoxycarbonylmethyl)-2'-deoxyuridine and ethylenediamine, 1,6-hexanediamine, or tris(2-aminoethyl)amine. The modified nucleosides were incorpo

Efficient Synthesis of New 5-Substituted Uracil Nucleosides Useful for Linker Arm Incorporation

5-Substituted uracil nucleosides useful for the attachment of linker arms to nucleic acids are prepared from arabinoaminooxazoline and dimethyl α-bromomethylfumarate in a short reaction sequence without using any protecting groups, and incorporated into o