170997-08-7Relevant academic research and scientific papers
New Efficient Strategy for the Incorporation of (S)-Isoserine into Peptides
Burger, Klaus,Windeisen, Elisabeth,Pires, Raul
, p. 7641 - 7645 (2007/10/03)
A new efficient synthesis of (S)-isoserine derivatives from (S)-malic acid using hexafluoroacetone as protecting and activating reagent is described.Via this route (S)-isoserine is obtained as mono- and diactivated species suitable for the incorporation of isoserine into the N- and C-terminal positions of peptides.
