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1710-66-3

1710-66-3

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1710-66-3 Usage

Uses

5-Isothiazolemethanol is used to prepare 1β-methylcarbapenems with isothiazoloethenyl side chains that exhibit antibaterial activities.

Check Digit Verification of cas no

The CAS Registry Mumber 1710-66-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,7,1 and 0 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1710-66:
(6*1)+(5*7)+(4*1)+(3*0)+(2*6)+(1*6)=63
63 % 10 = 3
So 1710-66-3 is a valid CAS Registry Number.
InChI:InChI=1/C4H5NOS/c6-3-4-1-2-5-7-4/h1-2,6H,3H2

1710-66-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,2-thiazol-5-ylmethanol

1.2 Other means of identification

Product number -
Other names Isothiazol-5-ylmethanol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1710-66-3 SDS

1710-66-3Relevant articles and documents

Synthesis and biological evaluation of novel 1β-methylcarbapenems with isothiazoloethenyl side chains

Kang, Yong Koo,Lee, Kyung Seok,Yoo, Kyung Ho,Shin, Kye Jung,Kim, Dong Chan,Lee, Chang-Seok,Kong, Jae Yang,Kim, Dong Jin

, p. 463 - 466 (2007/10/03)

The synthesis of novel 1β-methylcarbapenems 1a,b bearing isothiazoloethenyl moieties at C-5 position of pyrrolidine ring and their biological evaluation are described. Both compounds showed potent and well-balanced antibacterial activity as well as high stability to DHP-I. Especially, 5-isothiazole derivative 1a exhibited excellent DHP-I stability and advanced pharmacokinetics profiles, compared to 5-isoxazole derivative 2, imipenem, and meropenem.

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